Results 41 to 50 of about 1,715,473 (311)
Regulatory Cell Therapy in Organ Transplantation: Achievements and Open Questions
The effective development of innovative surgical applications and immunosuppressive agents have improved remarkable advancements in solid organ transplantation.
Marta Fortunato +5 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Automating fault tolerance in high-performance computational biological jobs using multi-agent approaches [PDF]
Background: Large-scale biological jobs on high-performance computing systems require manual intervention if one or more computing cores on which they execute fail.
Varghese, Blesson +2 more
core +1 more source
Effect of adjusting start tolerance and tolerance-norm of the Louvain algorithm for community detection. Louvain is an algorithm for detecting communities in graphs.
Subhajit Sahu
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Effect of using different values of tolerance with ordered PageRank algorithm for link analysis. Unordered PageRank is the standard way of computing PageRank computation, where two different rank vectors are maintained; one representing the current ranks
Subhajit Sahu
core +1 more source
Defect Tolerance in Hybrid nano/CMOS Architecture using Tagging Mechanism [PDF]
In this paper we propose two efficient repair techniques for hybrid nano/CMOS architecture to provide high level of defect tolerance at a modest cost.We have applied the proposed techniques to a lookup table(LUT) based Boolean logic approach.
Srivastava, Saket +5 more
core +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
AbstractThe role of plasticity in shaping adaptations is important to understanding the expression of traits within individuals and the evolution of populations. With increasing human impacts on the environment, one challenge is to consider how plasticity shapes responses to anthropogenic stressors such as contaminants. To our knowledge, only one study
Hua, Jessica +2 more
openaire +2 more sources

