Results 51 to 60 of about 1,513,260 (315)
F1000Research, 2018 Background: We previously identified the transcriptional regulator Zbtb32 as a factor that can promote T cell tolerance in the Non-Obese Diabetic (NOD) mouse, a model of Type 1 diabetes.
William D. Coley +6 more
doaj +1 more source
Tolerating the Conditionally Tolerant
Democratic Theory, 2020 How can a tolerant, liberal political culture tolerate the presence of only conditionally tolerant illiberal sub-cultures while remaining true to its principles of tolerance? The problem falls within the intersection of two developments in the thinking of two of the leading anglophone philosophers of the last half-century, Bernard Williams and John ...
openaire +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Ideas of Tolerance in Sixteenth Century France [PDF]
, 2005 This paper intend to revise ideas of tolerance in sixteenth century France. Discussions of tolerance have always caused confusion due to the fact that there has been no discernment between historical ideas, i.e., those used, in fact, in the early modern ...
3569 +3 more
core +1 more source
Screening of Non- Saccharomyces cerevisiae Strains for Tolerance to Formic Acid in Bioethanol Fermentation [PDF]
, 2015 Formic acid is one of the major inhibitory compounds present in hydrolysates derived from lignocellulosic materials, the presence of which can significantly hamper the efficiency of converting available sugars into bioethanol. This study investigated the
Phister, Trevor G. +31 more
core +1 more source
Maternal-fetal conflict averted by progesterone- induced FOXP3+ regulatory T cells
iScience, 2022 Summary: Pregnancy stimulates an intricately coordinated assortment of physiological changes to accommodate growth of the developing fetus, while simultaneously averting rejection of genetically foreign fetal cells and tissues.
Ashley L. Severance +9 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
School violence and teachers' perception of the zero tolerance policy [PDF]
, 2002 Plan BThis study examined teachers’ perception of the zero tolerance policy. The goal was to identify the benefits, drawbacks, and perceived effectiveness of the zero tolerance policy as a preventative tool against school violence.
Konter, Dana R.
core
Host genotype-specific rhizosphere fungus enhances drought resistance in wheat
MicrobiomeBackground The severity and frequency of drought are expected to increase substantially in the coming century and dramatically reduce crop yields.
Hong Yue +7 more
doaj +1 more source