Results 71 to 80 of about 1,772,991 (306)
BMC Plant BiologyCRISPR/Cas technologies have revolutionized plant genome editing, yet their inherent bias toward small insertions or deletions (indels) limits their utility for dissecting regulatory elements and generating impactful allelic variants. Here, we report the
Vikas Devkar +3 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
tolerance: An R Package for Estimating Tolerance Intervals [PDF]
The tolerance package for R provides a set of functions for estimating and plotting tolerance limits. This package provides a wide-range of functions for estimating discrete and continuous tolerance intervals as well as for estimating regression ...
Derek S. Young
core
Combined Time and Information Redundancy for SEU-Tolerance in Energy-Efficient Real-Time Systems
, 2006 Recently the trade-off between energy consumption and fault-tolerance in real-time systems has been highlighted. These works have focused on dynamic voltage scaling (DVS) to reduce dynamic energy dissipation and on time redundancy to achieve transient ...
Rosinger, Paul +4 more
core +1 more source
Evaluation of a new method for quantification of heat tolerance in different wheat cultivars
Journal of Integrative Agriculture, 2018 Heat stress seriously affects wheat production in many regions of the world. At present, heat tolerance research remains one of the least understood fields in wheat genetics and breeding and there is a lack of effective methods to quantify heat stress ...
Qiang LI +10 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Determinants of political tolerance : a literature review [PDF]
This paper reviews the current literature on political tolerance with particular reference to its individual- and aggregate-level determinants. Individual-level determinants such as authoritarianism, education, contact, and threat perception are found to
Hazama, Yasushi
core
ProceedingsBackground: The diverse cultures found worldwide have a significant impact on various aspects of mental health [...]
Mosabi Tolerance Ratsoma +2 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Salt leaching of heavy coastal saline silty soil by controlling the soil matric potential
Soil and Water Research, 2019 Techniques of drip irrigation are broadly applied for the reclamation of saline-alkali lands, during which effective management of water use to accelerate salt leaching is essential for crop production. In 2017, a field experiment with five treatments of
Xiuping Wang +5 more
doaj +1 more source