Results 81 to 90 of about 10,867,351 (301)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Approaches to Software Based Fault Tolerance - A Review [PDF]

open access: yesComputer Science Journal of Moldova, 2005
This paper presents a review work on various approaches to software based fault tolerance. The aim of this paper is to cover past and present approaches to software implemented fault tolerance that rely on both software design diversity and on single
Goutam Kumar Saha
doaj  

tolerance: An R Package for Estimating Tolerance Intervals [PDF]

open access: yes
The tolerance package for R provides a set of functions for estimating and plotting tolerance limits. This package provides a wide-range of functions for estimating discrete and continuous tolerance intervals as well as for estimating regression ...
Derek S. Young
core  

Determinant moments for the design management occurrence in fashion industry [PDF]

open access: yes, 2018
Design management has occupied a privileged place in debates related to the field of design and innovation in fashion industry. The apparel industry, in particular, presents a dynamic character, requiring constant updates on raw materials, changes in ...
Libânio, Cláudia de Souza   +5 more
core   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Defect Tolerance in Hybrid nano/CMOS Architecture using Tagging Mechanism [PDF]

open access: yes, 2009
In this paper we propose two efficient repair techniques for hybrid nano/CMOS architecture to provide high level of defect tolerance at a modest cost.We have applied the proposed techniques to a lookup table(LUT) based Boolean logic approach.
Srivastava, Saket   +5 more
core   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

RESEACH OF THREE-DIMENSIONAL CRACK GROWTH BASED ON DISK OF TURBO-SHAFT ENGINE

open access: yesJixie qiangdu, 2018
Three-dimensional crack growth was analyzed using damage tolerance design-based method and Franc3D to find cause of unexpected fatigue test failure of a turboshaft engine disk,showing that the crack propagation life was shorter than the test inspection ...
AI ShuMin   +3 more
doaj  

MOTOR TOLERANCE OPTIMIZATION DESIGN BASED ON IMPROVED GENETIC ALGORITHM

open access: yesJixie qiangdu, 2021
In order to improve the assembly quality of the motor and reduce the total cost,it is necessary to optimize the design of the tolerances of the key components that form the air gap between the motor stator and the rotor.
ZHANG YongLiang   +3 more
doaj  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

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