Results 81 to 90 of about 1,514,542 (307)
Designing fault-tolerant SOA based on design diversity [PDF]
Journal of Software Engineering Research and Development, 2014 Over recent years, software developers have been evaluating the benefits of both Service-Oriented Architecture (SOA) and software fault tolerance techniques based on design diversity. This is achieved by creating fault-tolerant composite services that leverage functionally-equivalent services.
Alexandre Nascimento +4 more
openaire +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Advances in Mechanical Engineering, 2017 The auto-body is usually composed of compliant sheet metals. The assembly variation is inevitable in the process of auto-body assembly. A reasonable tolerance allocation method for compliant sheet metal body parts is an important means to control ...
Sha Xu, Yanfeng Xing, Weifeng Chen
doaj +1 more source
ACEE composite structures technology [PDF]
Toppics addressed include: advanced composites on Boeing commercial aircraft; composite wing durability; damage tolerance technology development; heavily loaded wing panel design; and pressure containment and damage tolerance in ...
Johnson, Ronald W. +3 more
core +1 more source
Distributed operating systems [PDF]
, 1986 In the past five years, distributed operating systems research has gone through a consolidation phase. On a large number of design issues there is now considerable consensus between different research groups.\ud \ud In this paper, an overview of recent ...
Mullender, Sape J.
core +3 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
A Tolerance Type Screening Method Based on Similarity Evaluation
Applied SciencesIn the context of automatic generation methods for tolerance specifications, the current approach entails designers subjectively selecting geometric tolerances suitable for annotation from the tolerance types generated through automatic reasoning.
Guanghao Liu, Meifa Huang, Zhemin Tang
doaj +1 more source
Precision Die Design by The Die Expansion Method
The Proceedings of the Nigerian Academy of Science, 2013 A new method for the design of precision dies used in cold forging, extrusion and drawing processes is presented. It is based on die expansion. It attempts to provide a clear-cut theoretical basis for the selection of critical die dimensions for this ...
Akii O. Ibhadode FAS
doaj +1 more source
Fixture Design with FIXES: the Automatic Selection of Positioning, Clamping and Support Features for Prismatic Parts [PDF]
, 1989 FIXES is a computer aided system for the automatic generation of set-ups and for fixture design for prismatic parts, to be used in an integrated process planning environment.
Boerma, J.R., Kals, H.J.J.
core +2 more sources