Results 101 to 110 of about 445,386 (301)
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Background Soil salinization severely affects plant growth and development and has become one of the important abiotic stresses limiting crop growth. To improve soybean yield in saline soils, it is important to understand how soybean responds to salt ...
Wenkang Huang +7 more
doaj +1 more source
Single-event upset simulation and detection in configuration memory
Single-event upsets (SEUs) from radiation strikes in configuration memory are potentially catastrophic due to their widespread effects. For field-programmable gate arrays (FPGAs), faults in configuration memory propagate into the implemented logic design
Hezekiah Austin +8 more
doaj +1 more source
North East India Rice Genotypes: Screening of Arsenic Tolerant and Sensitive Rice at Germinating Stage [PDF]
Arsenic (As) accumulation in rice is hazardous to both plant and human because of its toxicity and carcinogenic properties. North-East (NE) rice genotypes (76) were screened at germination stage under As treatments (0, 50 and 100 µM) in order to discover
Thorny Chanu Thounaojam +3 more
doaj
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Cosmic-ray-induced correlated errors in superconducting qubit array
Correlated errors may devastate quantum error corrections that are necessary for the realization of fault-tolerant quantum computation. Recent experiments with superconducting qubits indicate that they can arise from quasiparticle (QP) bursts induced by ...
Xuegang Li +17 more
doaj +1 more source
Nitrogen deficiency is a key constraint on crop yield. Cassava, the world’s sixth-largest food crop and a crucial source of feed and industrial materials, can thrive in marginal soils, yet its yield is still significantly affected by limited nitrogen ...
Yu Wang +8 more
doaj +1 more source
The multifaceted roles of lysosomes in cancer
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
Model Perkuliahan Pendidikan Agama Islam Yang Damai, Moderat, dan Toleran
The study aims to describe the model of Islamic Religious Education (PAI) lectures that are peaceful, moderate, and tolerant in Indonesia University of Education (UPI). The research method used is descriptive-qualitative.
Munawar Rahmat
doaj +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source

