Results 101 to 110 of about 445,386 (301)

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Comparative transcriptome analysis reveals the complex response mechanisms of soybean leaves and roots to salt stress

open access: yesBMC Plant Biology
Background Soil salinization severely affects plant growth and development and has become one of the important abiotic stresses limiting crop growth. To improve soybean yield in saline soils, it is important to understand how soybean responds to salt ...
Wenkang Huang   +7 more
doaj   +1 more source

Single-event upset simulation and detection in configuration memory

open access: yesFrontiers in Space Technologies
Single-event upsets (SEUs) from radiation strikes in configuration memory are potentially catastrophic due to their widespread effects. For field-programmable gate arrays (FPGAs), faults in configuration memory propagate into the implemented logic design
Hezekiah Austin   +8 more
doaj   +1 more source

North East India Rice Genotypes: Screening of Arsenic Tolerant and Sensitive Rice at Germinating Stage [PDF]

open access: yesJournal of Stress Physiology & Biochemistry, 2019
Arsenic (As) accumulation in rice is hazardous to both plant and human because of its toxicity and carcinogenic properties. North-East (NE) rice genotypes (76) were screened at germination stage under As treatments (0, 50 and 100 µM) in order to discover
Thorny Chanu Thounaojam   +3 more
doaj  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Cosmic-ray-induced correlated errors in superconducting qubit array

open access: yesNature Communications
Correlated errors may devastate quantum error corrections that are necessary for the realization of fault-tolerant quantum computation. Recent experiments with superconducting qubits indicate that they can arise from quasiparticle (QP) bursts induced by ...
Xuegang Li   +17 more
doaj   +1 more source

Integrated transcriptomics and metabolomics analyses provide new insights into cassava in response to nitrogen deficiency

open access: yesFrontiers in Plant Science
Nitrogen deficiency is a key constraint on crop yield. Cassava, the world’s sixth-largest food crop and a crucial source of feed and industrial materials, can thrive in marginal soils, yet its yield is still significantly affected by limited nitrogen ...
Yu Wang   +8 more
doaj   +1 more source

The multifaceted roles of lysosomes in cancer

open access: yesMolecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Model Perkuliahan Pendidikan Agama Islam Yang Damai, Moderat, dan Toleran

open access: yesNadwa, 2018
The study aims to describe the model of Islamic Religious Education (PAI) lectures that are peaceful, moderate, and tolerant in Indonesia University of Education (UPI). The research method used is descriptive-qualitative.
Munawar Rahmat
doaj   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

open access: yesMolecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna   +8 more
wiley   +1 more source

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