Results 71 to 80 of about 14,603 (295)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Marvell Studies, 2018 You could be excused for thinking that rather than an Englishman, Andrew Marvell might better have been born a Dutchman in the republic’s golden age – an era of religious toleration and commercial ascendance, of fiscal accountability and civic ...
Steven Zwicker
doaj +2 more sources
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
, 2014 This chapter examines the philosophical and political problems associated with toleration. The philosophical problems relate to the nature and justification of toleration, while the political problems relate to the question of whether contemporary ...
Anna Elisabetta Galeotti
core +1 more source
A Far Cry from Pluralistic Individualism: Enlightenment Toleration Revisited
ReligionsIn order to highlight the unprecedented character of Enlightenment toleration theories and their decisive role in the intellectual history of modern freedoms, these theories are often depicted as principled, based on individual rights, and aimed at ...
Juan Pablo Domínguez
doaj +1 more source
Soldiers and ‘respect’ in complex conflicts: an Afghan case
Etikk i Praksis: Nordic Journal of Applied Ethics, 2017 This paper discusses the meaning of ‘respect’ in complex conflicts and aims to be a contribution to thinking about ethics in war along with the Just War tradition. The point of departure is the increased focus on soldiers as moral decision-makers in war,
Cornelia Vikan
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Toleration in Political Conflict
, 2013 Political disputes over toleration are endemic, while toleration as a political value seems opposed to those of civic equality, neutrality and sometimes democracy.
Newey, Glen Francis
core +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source