Results 81 to 90 of about 14,603 (295)

Unwanted yet Unavoidable Implementation of Religious Tolerance in Early Modern Transylvania

open access: yesCentral Europe, 2021
While most of early modern Europe was plunged into confessional strife, the central European principality of Transylvania managed to survive the period with no inter-confessional warfare.
Koloman Marschik
doaj  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Toleration and Political Philosophy

open access: yes, 2020
Toleration is a classic category of western political theory. Liberalism can be said to have evolved as a generalization of debates on religious toleration from the 17th century onwards.
Sune Lægaard, Lægaard, Sune; id_orcid
core   +1 more source

Néhány lelkigondozói szempont a türelem fogalmi megközelítéséhez

open access: yesStudia Universitatis Babeş-Bolyai. Theologia Reformata Transylvanica, 2019
Some Pastoral Aspects about Approach of Toleration’s Concept. Toleration has many concepts. One of these concepts can be one of pastoral care. Why do we need this?
Szilárd SÁNDOR
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

'To tolerate or not to tolerate?'

open access: yes, 2022
Many Western European countries have seen strong debates about minority rights and practices such as the founding of religious schools or the wearing of religious symbols in public institutions. In these increasingly diverse societies, tolerance of one another’s practices and beliefs has often been put forward as an indispensable ingredient for ...
openaire   +3 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Constantinian Toleration

open access: yes, 2018
Recent secular theorists of toleration have turned to Christian thought as a resource to overcome problems faced by secular-liberal accounts of toleration.
Vincent Lloyd
core   +1 more source

Originalitet og import i Holbergs oplysningstænkning

open access: yesSjuttonhundratal, 2014
Originality and Import in Holberg’s Enlightened Thinking. A figurehead of the Danish Enlightenment, Ludvig Holberg (1684–1754) was an intelligent and witty importer of ideas put into circulation by the founding fathers of the European Enlightenment ...
Thomas Bredsdorff
doaj   +1 more source

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