Results 101 to 110 of about 14,100 (247)
Holism, Inconsistency Toleration and Inconsistencies between Theory and Observation
Humana.Mente: Journal of Philosophical Studies, 2018 It has recently been argued by Davey (2014) that inconsistency is never tolerated in science, but only discretely isolated. But when talking about inconsistencies in science, not much attention has been paid to the inconsistencies between theory and ...
María del Rosario Martínez-Ordaz
doaj
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Irony and Toleration: Lessons from the Travels of Mendes Pinto
RUDN Journal of World History, 2009 Rebecca Catz argues that Fernao Mendes Pinto's «Peregrination», a sprawling account of travels in the East first published in 1614, is a «plea for toleration». Richard Rorty says that irony is a good mode for postmodern intellectual life.
J C Laursen
doaj
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
, 2017 Theoretical thesis.Bibliography: pages 65-71Chapter 1: Introduction -- Chapter 2: Kant & the German Terminology of Toleration -- Chapter 3: Toleration-Like Concepts in Kant -- Chapter 4: Evaluating the Secondary Literature on Kant’s View of Toleration --
Bain, Andrew McEwen
core
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Kasmera, 2000 : introduction: The main goal in this study was to know the efficacy of treatment with Secnidazole in schoolchildren acting as asymptomatic carriers of Giardia lumblia and Entamoela histolytica and also to evaluate its toleration.
Simoes M +10 more
doaj
Mémoires de la Saint-Barthélemy
Etudes EpistémèAt the start of the twenty-first century, 450 years after the massacre of St Bartholomew’s Day, the remembrance of this tragic ‘bloody night’ has re-emerged with force in the collective memory and in the public sphere. This revival is not just the result
Tatiana Debbagi Baranova +2 more
doaj +1 more source