Results 101 to 110 of about 72,239 (358)

NIETOLERANCYJNA KONFEDERACJA WARSZAWSKA. O ZNACZENIU SWOBÓD WYZNANIOWYCH W 1573 ROKU [PDF]

open access: yesKwartalnik Historyczny
The article considers the sig-nificance of the Warsaw Confederation, a document prepared during the interreg-num following the death of King Sigismund August in January 1573, from 1576 sworn to by kings of the Polish-Lithuanian Common ...
Maciej Ptaszyński
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

ОСОБЕННОСТИ ФОРМИРОВАНИЯ МЕЖНАЦИОНАЛЬНЫХ ОТНОШЕНИЙ В УСЛОВИЯХ ВЫСШЕГО УЧЕБНОГО ЗАВЕДЕНИЯ

open access: yesНаучно-педагогическое обозрение, 2018
Раскрываются некоторые особенности формирования межнациональных отношений в условиях поликультурного пространства высшего учебного заведения. Проанализированы современные научные подходы к проблеме межнациональных и межэтнических отношений в обществе и ...
Тихонова Елена Александровна
doaj   +1 more source

4. The Ideals of the Enlightenment

open access: yes, 1958
Among the ideals of the Enlightenment were nature, science, humanitarianism, cosmopolitanism, toleration, and progress. The ideals of any age are those ideas and principles to which men give their allegiance, and consequently ideals are a key to ...
Bloom, Robert L.   +6 more
core  

Gladstone, Religious Freedom and Practical Reasoning [PDF]

open access: yes, 2005
W.E. Gladstone’s changing and inconsistent views on religious oaths and established churches present an intriguing puzzle. This article compares and contrasts his early and later stances on these topics with the purpose of evaluating ...
Lorenzo, David J.
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Theological themes in Ricardo’s papers and correspondence [PDF]

open access: yes, 2017
I review evidence from published and unpublished sources on Ricardo’s theological ideas. The main focuses of interest are the existence of a natural morality independent of religious confessions, morality as the essence of religion, useless of ...
Cremaschi, Sergio Volodia Marcello
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Tradition and Prudence in Locke's Exceptions to Toleration [PDF]

open access: yes, 2003
Why did Locke exclude Catholics and atheists from toleration? Not, I contend, because he was trapped by his context, but because his prudential approach and practica ljudgments led him to traditiona ltexts.
Aristotle   +19 more
core   +1 more source

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