Results 151 to 160 of about 4,498,564 (240)
Immunology, Volume 179, Issue 3, Page 486-515, November 2026.In this study, we revealed the disturbed metabolic status of circulating and tumour‐infiltrating CD4+ and CD8+ T cells in melanoma patients through targeted metabolomic and lipidomic (on sorted subsets) and at single cell level using the SCENITH method.
Hugo Brouque +11 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 871-889, October 2026.The intestinal microbiome is a key regulator of immune homeostasis, metabolism, and epithelial barrier integrity. In patients with malignant hematological diseases, particularly those undergoing hematopoietic stem cell transplantation, microbiome perturbations by reduced diversity, pathobiont expansion, and loss of beneficial metabolites are common as ...
Bálint Gergely Szabó +7 more
wiley +1 more source
Tolerogenic dendritic cell-based immunotherapy
Oncotarget, 2017 Chang, Kiyuk +2 more
openaire +2 more sources
Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.First‐trimester trophoblast EVs are enriched in anti‐inflammatory proteins, lipids, and immunoregulatory miRNAs. EVT‐EVs reprogram monocytes toward a pro‐resolving phenotype and restore immune homeostasis in RDEB, supporting their potential as offering a scalable off‐the‐shelf therapy for chronic inflammatory diseases.
Nell Hirt +8 more
wiley +1 more source
MicrobiologyOpen, Volume 15, Issue 5, October 2026.The graphical abstract illustrates how microbiome‐derived indoles activate the aryl hydrocarbon receptor to restore the intestinal barrier. The picture contrasts the “leaky gut” state with the restored homeostasis achieved through AMPK, Nrf2, and IL‐22 signaling.
Mohammad Ali Mahdiabadi +2 more
wiley +1 more source
MedComm, Volume 7, Issue 10, October 2026.• EV content maintains cellular homeostasis and is involved in several disease onset and progression. • miRNA export in EVs depends on: RNA‐binding proteins recognizing motif sequences and on epitranscriptomic modifications. • The disclosure of delivery mechanisms is crucial for developing personalized EV‐based therapeutic tools. ABSTRACT Extracellular
Sabrina Garbo +4 more
wiley +1 more source
MedComm, Volume 7, Issue 10, October 2026.This review delineates the multifaceted roles of natural killer (NK) cells in the central nervous system, spanning direct cytolysis, immunoregulation, and crosstalk with the brain microenvironment. We evaluate the translational potential and challenges of NK cell immunotherapies for a spectrum of neurological conditions.
Kaihang Deng, Wai Po Chong
wiley +1 more source
Plasticity in gene expression programmes of dendritic cells responding to antigens. [PDF]
, 2005 Dendritic cells (DCs) are professional antigen presenting cells whose function is to initiate and shape an appropriate adaptive immune response. This requires an ability to distinguish differences between whole pathogens, in order to orchestrate ...
Kwan, A.P-Y., Kwan, Antonia Pui-Yue
core
MedComm, Volume 7, Issue 10, October 2026.Liver metastasis is a key driver of immune tolerance in patients with melanoma receiving immune checkpoint inhibitor therapy. This single‐arm phase II trial prospectively investigated the efficacy and safety of co‐ablation combined with sintilimab for liver metastatic melanoma.
Lujun Shen +11 more
wiley +1 more source
MedComm, Volume 7, Issue 10, October 2026.Alveolar macrophages: development, respiratory homeostasis, signal pathways, diseases, and therapeutic opportunities: During embryonic development, fetal progenitors migrate to the developing lungs via a CX3CR1‐dependent mechanism to establish the TrAM pool.
Sihan Yang +4 more
wiley +1 more source