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Regulation of adipogenesis by toll-like receptor 5 pathway

2016
Toll-like receptor 5 (TLR5) recognizes the bacterial product, flagellin. Its activation leads to cytokine production that is important for host defense against invading pathogens. In spite of the pro-inflammatory nature of TLR5, deficiency of TLR5 exacerbated metabolic dysfunction in diet-induced obese mouse model (Gewirtz et al. Science, 328: 228-231,
YIU, JHC, LI, J, Xu, A, Woo, WHC
openaire   +2 more sources

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

Nature, 2001
The innate immune system recognizes pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, but not on the host. Toll-like receptors (TLRs) recognize PAMPs and mediate the production of cytokines necessary for the development of effective immunity.
F, Hayashi   +9 more
openaire   +2 more sources

Regulation of osteoclastogenesis by toll-like receptor 5

Bone Abstracts, 2013
Ali Kassem   +4 more
openaire   +1 more source

Toll-like receptor 4 (TLR4) inhibitors: Current research and prospective

European Journal of Medicinal Chemistry, 2022
Xinjie Liang, Guoliang Chen
exaly  

Toll-Like Receptor 5 as a Novel Receptor for Fungal Zymosan

2023
Stefanie Reuter   +4 more
openaire   +1 more source

Assembly and localization of Toll-like receptor signalling complexes

Nature Reviews Immunology, 2014
Nicholas J Gay   +2 more
exaly  

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