Results 121 to 130 of about 2,286 (170)
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Polyurethane foam demonstrations: The unappreciated toxicity of toluene-2,4-diisocyanate
Journal of Chemical Education, 1974The author describes an accident and the relevant safety precautions resulting from a spill of toluene-2,4-diisocyanate .
G. W. Rayner. Canham, M. B. Hocking
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European Journal of Pharmacology, 1991 We have investigated the ability of ruthenium red, an inorganic dye with Ca2+ entry-blocking properties and a selective antagonist of capsaicin, and of indomethacin, a cyclooxygenase inhibitor, to inhibit bronchial smooth muscle responses evoked by ...
C E Mapp, Leonardo M Fabbri, J A Nadel
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Clinica Chimica Acta, 1983
A novel procedure to fix antibody on a plastic surface was developed, using a polystyrene tube treated with 0.5% toluene 2,4-diisocyanate (TC) dissolved in carbon tetrachloride. Using 125I-labelled IgG, we found that the rate of immobilization of IgG was significantly higher than that obtained by simple adsorption or coupling by glutaraldehyde in the ...
T, Saito, F, Nagai
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A novel procedure to fix antibody on a plastic surface was developed, using a polystyrene tube treated with 0.5% toluene 2,4-diisocyanate (TC) dissolved in carbon tetrachloride. Using 125I-labelled IgG, we found that the rate of immobilization of IgG was significantly higher than that obtained by simple adsorption or coupling by glutaraldehyde in the ...
T, Saito, F, Nagai
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Blocked isocyanate. Reaction and thermal behaviour of the toluene 2,4‐diisocyanate dimer
Die Angewandte Makromolekulare Chemie, 1996AbstractDue to the difference in reactivity between free isocyanates and uretdione rings, diisocyanate dimers can be used as blocked isocyanates. They offer the potential advantage that no volatile by‐products are formed. The toluene 2,4‐diisocyanate dimer contains one uretdione ring, formed by dimerization of two isocyanate groups, and two free ...
E. Querat +3 more
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Study on the synthesis of toluene-2,4-diisocyanate via amine and carbonyl fluoride
Journal of Fluorine Chemistry, 2015Abstract We presented recently a synthesis of toluene-2,4-diisocyanate (TDI) as one of the nine examples to verify the feasibility of an industrial appealing two-step method for isocyanates synthesis via amines and carbonyl fluoride (COF2). Because more investigation was considered to be necessary for future industrial application, the two-step ...
Ni Zhang +3 more
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Chain-extension and thermal behaviors of poly(p-dioxanone) with toluene-2,4-diisocyanate
Reactive and Functional Polymers, 2005Abstract A method for enhancing the molecular weight of poly( p -dioxanone) (PPDO) has been provided in this investigation. Higher molecular weight biodegradable polymers have been prepared by chain-extending method from lower molecular weight PPDO using toluene-2,4-diisocyanate (TDI) as a chain extender.
Qiao Lai +4 more
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Catalytic Effects of Water Clusters on the Hydrolysis of Toluene-2,4-diisocyanate: A DFT Study
Bulletin of the Chemical Society of Japan, 2015Abstract The reaction mechanism between 2,4-diisocyanatotoluene (2,4-TDI) and water clusters was carried out using density functional theory (DFT) at the B3LYP/6-311++G(d,p) level. The reaction can occur via two pathways. In path a, the 2,4-TDI reacts with water molecules by the attack across the N=C bond to form carbamic acid further ...
Yuan Yuan +6 more
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Toxicology and Applied Pharmacology, 1994
This study was initiated to evaluate the pharmacokinetics/metabolism of 14C-labeled toluene 2,4-diisocyanate (2,4-[14C]-TDI) following oral and inhalation exposure in the rat. For comparison, the pharmacokinetics/metabolism of toluene 2,4-diamine (2,4-[14C]TDA) was also evaluated. Groups of 3 or 4 male rats were given either a single 60 mg/kg oral dose
C, Timchalk, F A, Smith, M J, Bartels
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This study was initiated to evaluate the pharmacokinetics/metabolism of 14C-labeled toluene 2,4-diisocyanate (2,4-[14C]-TDI) following oral and inhalation exposure in the rat. For comparison, the pharmacokinetics/metabolism of toluene 2,4-diamine (2,4-[14C]TDA) was also evaluated. Groups of 3 or 4 male rats were given either a single 60 mg/kg oral dose
C, Timchalk, F A, Smith, M J, Bartels
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International Archives of Allergy and Immunology, 2005
<i>Background:</i> A toluene-2,4-diisocyanate (TDI)-induced asthma model, in which delayed-type hypersensitivity-like asthmatic airway obstruction is elicited restrictively in the lung, has never been developed. <i>Methods:</i> Guinea pigs were percutaneously sensitized with TDI.
Takeshi, Nabe +6 more
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<i>Background:</i> A toluene-2,4-diisocyanate (TDI)-induced asthma model, in which delayed-type hypersensitivity-like asthmatic airway obstruction is elicited restrictively in the lung, has never been developed. <i>Methods:</i> Guinea pigs were percutaneously sensitized with TDI.
Takeshi, Nabe +6 more
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Pharmacology, 2009
It is well known that starting treatment for cedar pollinosis therapy with second-generation antihistamines before the initial day of pollen scattering can relieve nasal symptom severity during the pollen season. Olopatadine hydrochloride (olopatadine) is an antiallergic agent with histamine H<sub>1</sub> receptor antagonistic action.
Tadafumi, Tamura, Naoya, Kimoto
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It is well known that starting treatment for cedar pollinosis therapy with second-generation antihistamines before the initial day of pollen scattering can relieve nasal symptom severity during the pollen season. Olopatadine hydrochloride (olopatadine) is an antiallergic agent with histamine H<sub>1</sub> receptor antagonistic action.
Tadafumi, Tamura, Naoya, Kimoto
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