Results 11 to 20 of about 2,286 (170)

Kujin Suppresses Histamine Signaling at the Transcriptional Level in Toluene 2,4-Diisocyanate–Sensitized Rats

Journal of Pharmacological Sciences, 2009
Kujin, the dried root of Sophorae flavescensis, has been used in Chinese folklore medicine against allergy. Evaluation of its anti-allergic potential as well as its mechanism of action has rarely been established. We investigated the effect of Kujin on toluene-2,4-diisocyanate (TDI)-induced allergic behavior and related histamine signaling including ...
Dev, Shrabanti, Mizuguchi, Hiroyuki, Das, Asish K., Maeyama, Kazutaka, Horinaga, Shiho, Kato, Shuhei, Tamada, Misaki, Hattori, Masashi, Umehara, Hayato, Fukui, Hiroyuki   +9 more
openaire   +5 more sources

Delayed Type Allergic Itch-Associated Response Induced by Toluene-2,4-diisocyanate in Hairless Mice

Journal of Pharmacological Sciences, 2003
To develop an allergic dermatitis model showing persistent scratching in mice, toluene-2,4-diisocyanate (TDI) was repeatedly painted onto the skin of hairless HR-1 mice, and induction of itch-associated scratching behavior was observed. When HR-1 mice were epicutaneously sensitized with 1% TDI and then challenged by repeated painting the cervicodorsal ...
Fuchibe, Kazuhiro, Nabe, Takeshi, Fujii, Masanori, Mizutani, Nobuaki, Danno, Kiichiro, Koda, Akihide, Kohno, Shigekatsu   +6 more
openaire   +5 more sources

Synthesis and Study of Gas Transport Properties of Polymers Based on Macroinitiators and 2,4-Toluene Diisocyanate

Membranes, 2019
Nowadays, block copolymers hold great promise for the design of novel membranes to be applied for the membrane gas separation. In this regard, microporous block copolymers based on a macroinitiator with an anionic nature, such as potassium-substituted ...
Ilsiya M. Davletbaeva, Ilnaz I. Zaripov, Alexander I. Mazilnikov, Ruslan S. Davletbaev, Raphael R. Sharifullin, Artem A. Atlaskin, Tatyana S. Sazanova, Ilya V. Vorotyntsev   +7 more
doaj   +2 more sources

Antihistamines suppress upregulation of histidine decarboxylase gene expression with potencies different from their binding affinities for histamine H1 receptor in toluene 2,4-diisocyanate-sensitized rats

Journal of Pharmacological Sciences, 2016
Antihistamines inhibit histamine signaling by blocking histamine H1 receptor (H1R) or suppressing H1R signaling as inverse agonists. The H1R gene is upregulated in patients with pollinosis, and its expression level is correlated with the severity of nasal symptoms. Here, we show that antihistamine suppressed upregulation of histidine decarboxylase (HDC)
Mizuguchi, Hiroyuki, Das, Asish K., Maeyama, Kazutaka, Dev, Shrabanti, Shahriar, Masum, Kitamura, Yoshiaki, Takeda, Noriaki, Fukui, Hiroyuki   +7 more
openaire   +4 more sources

Repeated Pre-treatment With Antihistamines Causes Transcriptional Up-regulations of Histamine H1 Receptor and Interleukin-4 Genes in Toluene-2,4-diisocyanate–Sensitized Rats

Journal of Pharmacological Sciences, 2008
Antihistamines are effective for treatment of seasonal nasal allergy. Recently, prophylactic treatment with antihistamines in patients with pollinosis was reported to be more effective when started before the pollen season. The administration with antihistamines from 2 to 6 weeks before onset of the pollen season is recommended for management of ...
Mizuguchi, Hiroyuki, Hatano, Masaya, Matsushita, Chiyo, Umehara, Hayato, Kuroda, Wakana, Kitamura, Yoshiyuki, Takeda, Noriaki, Fukui, Hiroyuki   +7 more
openaire   +5 more sources

Synthesis and research of polyfunctional silylureas used in electric deposition of tin-indium alloy

Chimica Techno Acta, 2021
Polyfunctional silylureas were synthesized by the interaction of 3-aminopropyltriethoxysilane with isocyanates of various structures in an inert aromatic solvent.
K. Yu. Ivanova, M. V. Kuzmin, L. G. Rogozhina, A. O. Patianova, V. L. Semenov, R. I. Alexandrov   +5 more
doaj   +1 more source

Curing Characteristics of Urethane-Dimethacrylate Homopolymers and Their Composites for Potential Application in Bone Cement

Engineering Proceedings, 2022
The polymerization of methacrylate compositions used in bone cement is often accompanied by a strong exothermic effect. The polymerizing mass heats up to very high temperatures at the cement application site, irritating the adjacent tissues and even cell
Marta W. Chrószcz-Porębska, Izabela M. Barszczewska-Rybarek   +1 more
doaj   +1 more source

β-Cyclodextrin conjugated bifunctional isocyanate linker polymer for enhanced removal of 2,4-dinitrophenol from environmental waters [PDF]

Royal Society Open Science, 2018
In this work, we reported the synthesis, characterization and adsorption study of two β-cyclodextrin (βCD) cross-linked polymers using aromatic linker 2,4-toluene diisocyanate (2,4-TDI) and aliphatic linker 1,6-hexamethylene diisocyanate (1,6-HDI) to ...
J. M. Anne, Y. H. Boon, B. Saad, M. Miskam, M. M. Yusoff, M. S. Shahriman, N. N. M. Zain, V. Lim, M. Raoov   +8 more
doaj   +1 more source

UHPLC-MS/MS Method for the Analysis of 2,6 Toluene Diisocyanate and 2,4 Toluene Diisocyanate Released from Microa-gglomerated Corks in Wine [PDF]

, 2021
Micro-agglomerate corks, made by agglutination of cork granulate through the addition of different adhesives, represent an important slice of the market of cork stoppers.
Corrias F., Cardu P., Cossu E., Angioni A.   +3 more
core   +1 more source

Synthesis and Characterization of Novel Nanoporous Gl-POSS-Branched Polymeric Gas Separation Membranes

Membranes, 2020
Novel nanoporous Gl-POSS-branched polymers based on the macroinitiator of anionic nature, 2,4-toluene diisocyanate, and octaglycidyl polyhedral oligomeric silsesquioxane (Gl-POSS) were obtained as gas separation membranes.
Ilnaz I. Zaripov, Ilsiya M. Davletbaeva, Zulfiya Z. Faizulina, Ruslan S. Davletbaev, Aidar T. Gubaidullin, Artem A. Atlaskin, Ilya V. Vorotyntsev   +6 more
doaj   +1 more source