Results 51 to 60 of about 7,203,845 (300)

AUTOMATIC TOOL PATH GENERATION IN CONTOUR MILLING USING GENETIC ALGORITHM [PDF]

, 2023
The purpose of this paper is to present new approach in automatic tool path generation in contour milling based on genetic algorithm and bitmap representation of work piece and additional resources. It deals with the problem of tool path generation and
Zahar Djordjevic, Marija, Mitić, Predrag, Abadić, Nebojša, Petronijević, Vuk, Djordjevic, Aleksandar   +4 more
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Constant scallop height tool path generation [PDF]

, 1989
journal articleAn approach for the automatic generation of constant scallop height tool paths is presented. An example is shown generated from a B-spline model, although it can be used with many types of sculptured surfaces. The approach utilizes surface
Chou, Jin J., Cohen, Elaine
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Intelligent process planning and control of DED (directed energy deposition) for rapid manufacturing

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2020
This research has been conducted to develop computer aided manufacturing software, which can generate NC programs for a five-axis directed energy deposition (DED) type additive manufacturing system with following three focuses: 1.
Masahiro UEDA, David CARTER, Kazuo YAMAZAKI, Yasuhiro KAKINUMA   +3 more
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Process simulation integrated tool axis selection for 5-axis tool path generation

, 2016
In 5-axis tool path generation the tool axis is usually selected based on the workpiece geometry only, ignoring its effects on the process and machine tool motion. In this paper, a process simulation integrated tool axis selection approach is proposed to
Budak, Erhan, Bilgen, Samet, Tunç, Lütfi Taner, Zatarain, Mikel   +3 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Incomplete mesh-based tool path generation for optimum zigzag milling

, 2008
The majority of mechanical parts are manufactured by milling machines. Hence, geometrically efficient algorithms for tool path generation and physical considerations for better machining productivity with guarantee of machining safety are the most ...
Kim, Hyun-Chul, Hyun-Chul Kim, Min-Yang Yang, Yang, Min-Yang   +3 more
core   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source