Results 51 to 60 of about 90,035 (265)

Research and Application of CNC Machining Method Based on CAD/CAM/Robot Integration

open access: yesAdvances in Multimedia, 2022
In order to improve the effect of intelligent CNC machining, this paper combines the CAD/CAM/Robot integration method to improve the CNC machining method and analyzes the tool path planning method and the path generation algorithm of the five-axis CNC ...
Xiangsong Yan
doaj   +1 more source

Investigation of Cutting Path Effect on Spindle Vibration and AE Signal Features for Tool Wear Monitoring in Micro Milling

open access: yesApplied Sciences, 2023
In the development of a tool wear monitoring system in milling, the complex cutting path always brings challenges to the system’s reliability in the production line.
Ci-Rong Huang, Ming-Chyuan Lu
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

End-to-End Tool Path Generation for Triangular Mesh Surfaces in Five-Axis CNC Machining

open access: yesAppliedMath
Triangular mesh surface representation is widely adopted in geometric design and reverse engineering applications. However, in high-precision Computer Numerical Control (CNC) machining, significant limitations persist in automated Computer-Aided ...
Shi-Chu Li   +3 more
doaj   +1 more source

Tool-Path Problem in Direct Energy Deposition Metal-Additive Manufacturing: Sequence Strategy Generation

open access: yesIEEE Access, 2020
The tool-path problem has been extensively studied in manufacturing technologies, as it has a considerable impact on production time. Additive manufacturing is one of these technologies; it takes time to fabricate parts, so the selection of optimal tool ...
Maialen Murua   +3 more
doaj   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Optimal Joint Path Planning of a New Virtual-Linkage-Based Redundant Finishing Stage for Additive-Finishing Integrated Manufacturing

open access: yesMathematics, 2023
This paper describes the optimal path planning of a redundant finishing mechanism developed for joint space-based additive-finishing integrated manufacturing (AFM). The research motivation results from an inevitable one-sided layout of a finishing stage (
Jiwon Yu   +3 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Intelligent process planning and control of DED (directed energy deposition) for rapid manufacturing

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2020
This research has been conducted to develop computer aided manufacturing software, which can generate NC programs for a five-axis directed energy deposition (DED) type additive manufacturing system with following three focuses: 1.
Masahiro UEDA   +3 more
doaj   +1 more source

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