Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
A framework from point clouds to workpieces
Visual Computing for Industry, Biomedicine, and Art, 2022 Combining computer-aided design and computer numerical control (CNC) with global technical connections have become interesting topics in the manufacturing industry.
Li-Yong Shen +4 more
doaj +1 more source
Método de geração de trajetórias trocoidais e espirais combinadas para o fresamento de desbaste de cavidades 2,5D com múltiplas ferramentas [PDF]
, 2013 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-graduação em Engenharia Mecânica, Florianópolis, 2013Para o fresamento de cavidades as estratégias de geração de trajetórias mais utilizadas são a ...
Ochoa Gonzáles, David Manuel
core
FEBS Open Bio, EarlyView.Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Modelling and simulation of the dynamic cutting process and surface topography generation in nano/micro cutting [PDF]
, 2008 In nano/micro cutting process, the surface quality is heavily dependent on all the dynamic factors in machining including those from the material, tooling, cutting parameters, servo accuracy, mechanical structure deformation, and non-linear factors as ...
Cheng, K, Zhou, L
core +4 more sources
5-axis tool path generation with collision detection for finish machining of freeform surfaces [PDF]
, 2012 Research in the field of Tool path generation for freeform surfaces has been done intensively in the past. However, the main challenge that still exists is the computational efficiency related to the tool path generation.
Francis, Jomy
core +1 more source
Smart tool path generation for 5-axis ball-end milling of sculptured surfaces using process models
, 2019 Efficient 5-axis milling of free form surfaces required smart parameter selection and tool path generation approaches. Current computer-aided manufacturing (CAM) technology offers limited flexibility and assistance for such purposes, where purely ...
Tunç, Lütfi Taner
core +1 more source
Tool Path Generation for Flexible Blade Cutting [PDF]
, 2000 Free Form Thick Layered Object Manufacturing FF-TLOM is based on application of a reshapeable cutting device, which allows a free form shaping of thick polystyrene foam layers. Once manufactured, these layers are stacked to produce a physical model. Tool
Smit, Bram de +2 more
core +1 more source
Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1
FEBS Open Bio, EarlyView.The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn +2 more
wiley +1 more source