Results 101 to 110 of about 381,354 (308)

Osteogenic mechanism of chlorogenic acid and its application in clinical practice

Frontiers in Pharmacology
Natural polyphenols may have a role in counteracting oxidative stress, which is associated with aging and several bone-related diseases. Chlorogenic acid (CGA) is a naturally occurring polyphenolic compound formed by the esterification of caffeic and ...
Jiayu Shen, Jiayu Shen, Shichen Zhang, Shichen Zhang, Jiayu Zhang, Jiayu Zhang, Xin Wei, Xin Wei, Zilin Wang, Zilin Wang, Bing Han, Bing Han   +11 more
doaj   +1 more source

Unveiling a New Link: Cholesterol Deficiency in Smith–Lemli–Opitz and Niemann–Pick C as a Driver of Ciliopathies

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The ciliopathies are a group of genetic disorders caused by defective function of either the primary cilia (a large number) or the motile cilia (a much smaller number). These have been defined as diseases with mutations in genes encoding individual ciliary or cilia‐associated proteins.
Robert P. Erickson, Maria Teresa Fiorenza   +1 more
wiley   +1 more source

Reduction of gear pair transmission error with tooth profile modification [PDF]

, 2008
The gear noise problem that widely occurs in power transmission systems is typically characterised by one or more high amplitude acoustic signals. The noise originates from the vibration of the gear pair system caused by transmission error excitation ...
Alfano, G, Atherton, MA, Tharmakulasingam, R   +2 more
core  

Human Leukocyte Elastase Triggered Nanoparticles for Targeted Antimicrobial Delivery and Oral Microbial Modulation

Advanced NanoBiomed Research, EarlyView.
This study explores enzyme‐responsive nanoparticles for targeted antimicrobial release in inflamed oral environments. Nanoparticles formed by complexing peptides and chlorhexidine respond to human leukocyte elastase and release chlorhexidine selectively. P7 (ECAAPVCE)‐based formulations show optimal properties and stability, with antimicrobial activity
Mohammed A. Hadis, Ignacio Insua, Farah N. S. Raja, Álvaro Vila, William M. Palin, Michael R. Milward, Paul R. Cooper, Sarah A. Kuehne, Owen Addison, Paco Fernandez‐Trillo   +9 more
wiley   +1 more source

Functional morphology of the pharyngeal teeth of the ocean sunfish, Mola mola

The Anatomical Record, EarlyView.
Abstract Many fish use a set of pharyngeal jaws in their throat to aid in prey capture and processing, particularly of large or complex prey. In this study—combining dissection, CT scanning, histology, and performance testing—we demonstrate a novel use of pharyngeal teeth in the ocean sunfish (Mola mola), a species for which pharyngeal jaw anatomy had ...
Benjamin Flaum, Michael J. Blumer, Mason N. Dean, Laura J. Ekstrom   +3 more
wiley   +1 more source

Finite element analysis of feeding in red and gray squirrels (Sciurus vulgaris and Sciurus carolinensis)

The Anatomical Record, EarlyView.
Abstract Invasive gray squirrels (Sciurus carolinensis) have replaced the native red squirrel (Sciurus vulgaris) across much of Great Britain over the last century. Several factors have been proposed to underlie this replacement, but here we investigated the potential for dietary competition in which gray squirrels have better feeding performance than ...
Philip G. Cox, Peter J. Watson
wiley   +1 more source

Homeostasis and imbalance of calcium dynamics in osteocytes

Kouqiang hemian waike zazhi
The skeleton is a dynamically changing organ, and its homeostasis is maintained through the precise perception and response of osteocytes to mechanical load. The Ca2+ signal, as an early key signal in this process, can convert external mechanical signals
NIE Mengdong, QIANG Jinbiao, SHI Ce
doaj   +1 more source

Tooth eruption status and bite force determine dental microwear texture gradients in albino rats (Rattus norvegicus forma domestica)

The Anatomical Record, EarlyView.
Abstract Dental microwear texture analysis (DMTA) is widely applied for inferring diet in vertebrates. Besides diet and ingesta properties, factors like wear stage and bite force may affect microwear formation, potentially leading to tooth position‐specific microwear patterns.
Daniela E. Winkler, Isabelle Bernetière, Christine Böhmer   +2 more
wiley   +1 more source

KMT2D Regulates Tooth Enamel Development

Journal of Dental Research
Amelogenesis, the process of enamel formation, is tightly regulated and essential for producing the tooth enamel that protects teeth from decay and wear. Disruptions in amelogenesis can result in amelogenesis imperfecta, a group of genetic conditions characterized by defective enamel, including enamel hypoplasia, marked by thin or ...
J.-M. Lee, H. Jung, Q. Tang, L. Li, S.-K. Lee, J.W. Lee, Y. Park, H.-J.E. Kwon   +7 more
openaire   +2 more sources

Mesalazine: a novel therapeutic agent for periodontitis via regulation of periodontal microbiota and inhibiting Porphyromonas gingivalis

Frontiers in Microbiology
IntroductionPeriodontitis and inflammatory bowel disease are chronic inflammatory diseases with shared epidemiological, biological, and therapeutic associations. Given the similarities in their pathogenic factors, this study hypothesized that mesalazine,
Yuqi Wang, Yuqi Wang, Jun Ma, Haoyu Wang, Haoyu Wang, Jingzheng Yi, Yuxin Bai, Yuxin Bai, Min Hu, Min Hu, Jiaqing Yan, Jiaqing Yan   +11 more
doaj   +1 more source