Results 111 to 120 of about 9,334,973 (302)

SFTopk: Secure Functional Top- $k$ Query via Untrusted Data Storage

open access: yesIEEE Access, 2015
Providing top-k query services is relevant for storage servers which collect valuable files/data and process queries for data owners and mobile users.
Yao-Tung Tsou   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Differentiable Top-k Classification Learning

open access: yes, 2022
The top-k classification accuracy is one of the core metrics in machine learning. Here, k is conventionally a positive integer, such as 1 or 5, leading to top-1 or top-5 training objectives.
Kuehne, Hilde   +3 more
core   +1 more source

Top-k trajectories with the best view

open access: yes, 2019
The widespread availability of GPS and the growing popularity of location based social networking applications such as Flickr, Yelp, etc., enable more and more users to share their route activities or trajectories.
Mahjabin Nahar (20066451)   +5 more
core  

Top-$k$ Feature Importance Ranking

open access: yesCoRR
Accurate ranking of important features is a fundamental challenge in interpretable machine learning with critical applications in scientific discovery and decision-making. Unlike feature selection and feature importance, the specific problem of ranking important features has received considerably less attention.
Eric Chen   +2 more
openaire   +3 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

ACCF:Time Prediction Mechanism-driven Top-k Flow Measurement [PDF]

open access: yesJisuanji kexue
In addressing the problem that current top-k flow measurement filtering algorithms depend on fixed counter thresholds,a measurement structure named ACCF based on the activity prediction mechanism has been put forward.ACCF incorporates the activity ...
HU Yongqing, YANG Han, LIU Ziyuan, QING Guangjun, DAI Qinglong
doaj   +1 more source

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