Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
"The emperor's new clothes": a qualitative study of end users' experiences from a failed large-scale implementation of an electronic health record system. [PDF]
Dannapfel P, Axelsson A, Gustavsson SMK.
europepmc +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Do no harm? How health care management research can advance environmentally sustainable health care. [PDF]
Tietschert MV +5 more
europepmc +1 more source
BIM-Supported green building adoption in the construction industry. [PDF]
Alrasheed KA +5 more
europepmc +1 more source
Accommodation of Biodiversity in Swedish Municipalities. A National Survey. [PDF]
Christoffersen L, Englund JE, Randrup T.
europepmc +1 more source
The deployment of semiochemical-based pest management tools for woody plants in managed residential and commercial landscapes: current status, challenges, and future directions. [PDF]
Rigsby CM +6 more
europepmc +1 more source
Factors Influencing Intention to Leave Among Nurse Managers: A Cross-Sectional Study. [PDF]
Simonetti V +8 more
europepmc +1 more source

