Results 101 to 110 of about 1,627,101 (285)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Top Quark Physics

open access: yes, 2000
111 pages, Latex, to appear in the Report of the ``1999 CERN Workshop on SM physics (and more) at the LHC'', M.Beneke, I.Efthymiopoulos, M.L.Mangano, J.Womersley (conveners)
Beneke, M.   +77 more
openaire   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Physics objects for top quark physics in ATLAS

open access: yes, 2016
Top quark physics measurements performed using data from the ATLAS detector at the LHC rely on efficient reconstruction and precise calibration of leptons, jets and missing transverse energy. A review of the techniques used to reconstruct such objects is
Hawkings, Richard
core  

Isospin Breaking and the Top-Quark Mass in Models of Dynamical Electroweak Symmetry Breaking

open access: yes, 1995
In this talk we review the physics of top-quark mass generation in models of dynamical electroweak symmetry breaking and the constraints on this physics arising from limits on the deviation of the weak interaction $\rho$-parameter from one.
Chivukula, R. Sekhar   +2 more
core   +1 more source

TOP QUARK PHYSICS AT CDF

open access: yesFundamental Interactions, 2005
The existence of the top quark, discovered by CDF and D0 in 1995, has been re-established in the burgeoning dataset being collected in Run 2 of the Tevatron at Fermilab. Results from CDF on the top quark production cross section and top quark mass are consistent with the Standard Model expectations.
openaire   +2 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Top physics prospects at LHC

open access: yes, 2005
With a high instantaneous luminosity and the large top quark pair production cross section, the Large Hadron Collider (LHC) will be a "top factory" allowing the analysis of millions of top events.
Beaudette, Florian
core  

Top quark physics in hadron collisions

open access: yes, 2005
The top quark is the heaviest elementary particle observed to date. Its large mass makes the top quark an ideal laboratory to test predictions of perturbation theory concerning heavy quark production at hadron colliders.
Abazov V M   +63 more
core   +3 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

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