Results 41 to 50 of about 2,055 (160)

A Metabolomic Signature Predicts Gout Flare Clinical Outcome Associated With Colchicine Prophylaxis

Arthritis &Rheumatology, Volume 78, Issue 8, Page 1765-1775, August 2026.
Objective This study investigated that serum metabolomics, before urate‐lowering therapy (ULT) initiation, could serve as a biomarker for responsiveness to colchicine prophylaxis in patients with gout commencing treat‐to‐target ULT. Methods We studied a multicenter prospective cohort (n = 409) initiating treat‐to‐target ULT plus colchicine prophylaxis.
Wenyan Sun, Lingfang Xu, Haibing Chen, Mingshu Sun, Zhiqiang Li, Rui Li, Lidan Ma, Hui Zhang, Aichang Ji, Yuwei He, Na Wu, Le Yan, Robert Terkeltaub, Changgui Li   +13 more
wiley   +1 more source

Spinal gout causing reversible quadriparesis: a case report and literature review

Journal of Community Hospital Internal Medicine Perspectives, 2018
Gout commonly affects peripheral joints and is rarely found in axial joints, such as the spine and sacroiliac joints. We report a case of a patient that presented with quadriparesis who was empirically treated for spinal gout and a review of relevant ...
Jaspreet Kaler, Osama Mukhtar, Mazin Khalid, Shivani Thapa, Ravinder Kaler, Brandon Ting, Vijay Gayam   +6 more
doaj   +1 more source

Tophaceous Gout with Atypical Localization without Hyperuricemia or an Inflammatory Gout Attack

The Turkish Journal of Gastroenterology, 2013
Tophaceous gout which typically develops following recurrent acute attacks, accounts for 10% of all gout cases. Although gout is known as a condition which primarily affects male gender, 5% of the patients are women with the majority being ...
Hacı Bayram TOSUN, Sancar SERBEST, Murat BALOĞLU, Mustafa Erkan İNANMAZ, Kamil Çağrı KÖSE   +4 more
doaj  

Chronic tophaceous gout causing lumbar spinal stenosis

Radiology Case Reports, 2021
Gout is a common cause of inflammatory arthritis, typically affecting the joints of the appendicular skeleton. In this report, we present the relatively less common scenario of chronic tophaceous gout affecting the lumbar spine and pelvis, complicated by
Samantha Ayoub, MD, Anandh G. Rajamohan, MD, Jay Acharya, MD, Jordan Gross, MD, Vishal Patel, MD, PhD   +4 more
doaj   +1 more source

Multiarticular chronic tophaceous gout with severe and multiple ulcerations: a case report

Journal of Medical Case Reports, 2011
Introduction Gout is a common inflammatory arthritis caused by articular precipitation of monosodium urate crystals. It usually affects the first metatarsophalangeal joint of the foot and less commonly other joints, such as wrists, elbows, knees and ...
Pavlakis Emmanouil, Mathioulakis Stavros, Bournia Vasiliki-Kalliopi, Rallis Efstathios, Falidas Evangelos, Villias Constantinos   +5 more
doaj   +1 more source

Factors Associated With Intermittent and Constant Pain Patterns in People With Gout: A Cross‐Sectional Analysis

ACR Open Rheumatology, Volume 8, Issue 7, July 2026.
Objective Although gout is traditionally conceptualized as an episodic disease characterized by acute flares and symptom‐free intercritical periods, some individuals report persistent joint pain that extends beyond flares. This cross‐sectional analysis aimed to explore factors associated with self‐reported pain patterns (constant vs intermittent) in ...
Sarah Stewart, Mia Clarke, Irene Zeng, Nicola Dalbeth, Tania Ka'ai, Karl Rudolph, Julie Collis, Nicola Kayes, David Rice   +8 more
wiley   +1 more source

Blood Biomarkers and Surface‐Enhanced Raman Spectroscopy for Gout: A Comprehensive Review

Advanced Functional Materials, Volume 36, Issue 51, 25 June 2026.
Schematic illustrating gout disease progression from asymptomatic hyperuricemia to chronic tophaceous disease, highlighting the limitations of conventional imaging and biochemical diagnostics and the potential of engineered SERS platforms for ultrasensitive blood‐based detection of urate‐related biomarkers across disease stages, with the color gradient
Isuri Perera, Chiranjeevi Kanike, Appurva Tiwari, Hongyan Wu, Larry D. Unsworth, Ben Bin Xu, Xuehua Zhang   +6 more
wiley   +1 more source

Atypical erosive tophaceous gout with severe osteolysis around multiple joints of the digits: A case report

Journal of Orthopaedic Reports, 2022
Introduction: Gout is a chronic metabolic disorder secondary to hyperuricemia and is typically characterized initially by monoarticular arthritis starting at the distal extremities and may progress to tophaceous gout after several years of acute attacks ...
Magtoto Ian Jason, Keiichi Muramatsu, Yasuhiro Tani, Masato Kobayashi   +3 more
doaj   +1 more source

Long‐Term Opioids in Gout: A Matched Cohort Study From the Veterans Health Administration

Arthritis Care &Research, Volume 78, Issue 3, Page 344-351, March 2026.
Objective Though used frequently to treat flare, risk of long‐term opioid exposure in gout has not been well defined. In this study, we examined the hypothesis that people with gout are more likely than individuals without gout to be prescribed long‐term opioids over time.
Lindsay N. Helget, Bryant R. England, Punyasha Roul, Harlan Sayles, Tuhina Neogi, James R. O'Dell, Joshua F. Baker, Ted R. Mikuls   +7 more
wiley   +1 more source

Long‐term remission in gout: Challenges and future opportunities

Rheumatology &Autoimmunity, Volume 6, Issue 1, Page 7-15, March 2026.
Prolonged hyperuricemia is a major risk factor for gout, which is now regarded as a curable disease. Awareness of the various factors that can trigger gout flares is essential for their prevention. An important determinant of treatment decisions and long‐term follow‐up is the quality of the clinician–patient relationship. The “treat‐to‐target” approach
Patapong Towiwat, Zhanguo Li
wiley   +1 more source