Results 51 to 60 of about 3,852 (209)

Ultrasound Findings in Symptomatic HADD of the Hand and Wrist. A Case Series of 37 Patients

Journal of Clinical Ultrasound, EarlyView.
Ultrasound enables accurate diagnosis of hydroxyapatite deposition disease of the hand and wrist in patients with acute, non‐traumatic pain, typically in middle‐aged women. Characteristic calcifications, often in the resorptive phase, support diagnosis, while radiography may confirm findings without the need for advanced imaging.
Marco Becciolini, Riccardo Picasso, Antonio Corvino, Federico Zaottini   +3 more
wiley   +1 more source

Clinical characteristics and risk factors associated with bone erosion in patients with tophi

Advances in Rheumatology
Introduction If a large amount of urate crystals is deposited in a joint cavity for an extended period of time, bone erosion will occur and gradually cause skeletal muscle necrosis and joint deformity.
Zhuyi Ji, Yukai Huang, Ling Liang, Paifeng Lin, Xin Guo, Qidang Huang, Zhengping Huang, Shuyang Chen, Zhixiang Huang, Biao Wang, Lixin Huang, Shanmiao Sun, Weiming Deng, Tianwang Li   +13 more
doaj   +1 more source

When Joint Aspiration Fails: Point‐of‐Care Ultrasound for Diagnosing Chronic Gout in Prolonged Monoarthritis

Journal of General and Family Medicine, Volume 27, Issue 5, September 2026.
ABSTRACT Background A 34‐year‐old man presented to our primary care clinic with persistent pain and swelling of the right first metatarsophalangeal joint lasting 3 months. A previous clinic had suspected gout based on hyperuricemia, but urate‐lowering therapy was repeatedly withheld because of ongoing inflammation, resulting in prolonged symptoms ...
Takayuki Yamada
wiley   +1 more source

Characteristics of ocular abnormalities in gout patients

International Journal of Ophthalmology, 2013
AIM: To characterize the clinical features of ocular surface in gout patients in coastal area of Shandong Province in China.METHODS: A total of 380 consecutive gout patients were examined from January 2011 to May 2011.
Chang-Gui Li, Qian Wang, Shan-Shan Yang, Cheng-Ye Che, Gui-Qiu Zhao, Jing Lin   +5 more
doaj   +1 more source

Multiple symmetric lipomatosis with chronic kidney disease and tophi [PDF]

, 2023
Ruqi Tan, Pearl Pai
openalex   +1 more source

Tofos gotosos volumosos

Galicia Clínica, 2019
Gout results from the deposition of uric acid crystals at various locations (preferably joints, subcutaneous tissue, and kidney). About seven percent of the adult population develop hyperuricemia, but only about one percent progress to gout.
Joana Oliveira, Rodolfo Gomes
doaj   +1 more source

A Metabolomic Signature Predicts Gout Flare Clinical Outcome Associated With Colchicine Prophylaxis

Arthritis &Rheumatology, Volume 78, Issue 8, Page 1765-1775, August 2026.
Objective This study investigated that serum metabolomics, before urate‐lowering therapy (ULT) initiation, could serve as a biomarker for responsiveness to colchicine prophylaxis in patients with gout commencing treat‐to‐target ULT. Methods We studied a multicenter prospective cohort (n = 409) initiating treat‐to‐target ULT plus colchicine prophylaxis.
Wenyan Sun, Lingfang Xu, Haibing Chen, Mingshu Sun, Zhiqiang Li, Rui Li, Lidan Ma, Hui Zhang, Aichang Ji, Yuwei He, Na Wu, Le Yan, Robert Terkeltaub, Changgui Li   +13 more
wiley   +1 more source

Disseminated Chronic Tophaceous Gout With Multi‐Tissue Involvement

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Gout is a metabolic condition in which hyperuricaemia leads to deposition of monosodium urate (MSU) crystals in synovial and peri‐articular tissues. (1) Acutely, synovial deposition causes a painful inflammatory reaction. Over time, chronic hyperuricaemia can lead to deposition of uric acid crystals in alternate tissues, with granulomatous ...
Yee Leng Loh, Fiona Combe
wiley   +1 more source

Nucleotide Metabolism in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Nucleotide metabolism, including de novo synthesis, salvage pathways, and catabolism, when dysregulated contributes to cancer, immune disorders, metabolic and urological diseases, and radiation injury. Metabolites such as adenosine, cGAMP, NAD, and cAMP and enzymes like RNR are promising therapeutic targets and biomarkers.
Xiaoying Zhao, Yiyu Zeng, Yike Xu, Shu Rao, Mouna Khouchani, Hassna Soummane, Jingyi Li, Rui Liu   +7 more
wiley   +1 more source

Factors Associated With Intermittent and Constant Pain Patterns in People With Gout: A Cross‐Sectional Analysis

ACR Open Rheumatology, Volume 8, Issue 7, July 2026.
Objective Although gout is traditionally conceptualized as an episodic disease characterized by acute flares and symptom‐free intercritical periods, some individuals report persistent joint pain that extends beyond flares. This cross‐sectional analysis aimed to explore factors associated with self‐reported pain patterns (constant vs intermittent) in ...
Sarah Stewart, Mia Clarke, Irene Zeng, Nicola Dalbeth, Tania Ka'ai, Karl Rudolph, Julie Collis, Nicola Kayes, David Rice   +8 more
wiley   +1 more source