Results 71 to 80 of about 4,180 (201)
Galicia Clínica, 2019 Gout results from the deposition of uric acid crystals at various locations (preferably joints, subcutaneous tissue, and kidney). About seven percent of the adult population develop hyperuricemia, but only about one percent progress to gout.
Joana Oliveira, Rodolfo Gomes
doaj +1 more source
Nucleotide Metabolism in Health and Disease
MedComm, Volume 7, Issue 8, August 2026.Nucleotide metabolism, including de novo synthesis, salvage pathways, and catabolism, when dysregulated contributes to cancer, immune disorders, metabolic and urological diseases, and radiation injury. Metabolites such as adenosine, cGAMP, NAD, and cAMP and enzymes like RNR are promising therapeutic targets and biomarkers.
Xiaoying Zhao +7 more
wiley +1 more source
Tophi as first manifestation of gout
Indian Journal of Dermatology, Venereology, and Leprology, 2010 Chronic tophaceous gout classically occurs after 10 years or more of recurrent polyarticular gout. However, tophi can also occur as first sign of the disorder. Here we report a 20-year-old male presenting with multiple subcutaneous nodules on bilateral feet and toes, left palm, right elbow, helix of left ear since last one and half year prior to any ...
Sankha, Koley +5 more
openaire +2 more sources
The Turkish Journal of Gastroenterology, 2019 Objectives: This study aims to establish cardiovascular risk in obese and non-obese patients in stages of gout by using Framingham risk score (FRS) and transthoracic echocardiography.
Rada GANCHEVA +4 more
doaj
Journal of Inflammation Research, 2021 Zhen Gong,1 Li Xia,1 Rune Xu,1 Min Luo,1 Hongxiang Deng,1 Zhiping Kang,1 Leping Liu,1 Yaqing Liu,1 Fangjie Zhang,2 Jian Shi1 1Department of Rheumatology, Yiyang Central Hospital, Yiyang, Hunan, People’s Republic of China; 2Department of Emergency ...
Gong Z +9 more
doaj
, 2017 Gouty tophi represent a symptom of chronic form of gout resulting from accumulation ofmonosodium urate crystals in tissues, which is the most prevalent form of inflammatory arthritis.The tophus represents a granulomatous inflammatory response to ...
Gonzalo Cabezón-Villalba +3 more
core
A case of severe gouty tophi-induced carpal tunnel syndrome: Operative finding and its outcome
, 2018 IntroductionGout is a disease featuring acute arthritis, joint deformity and severe pain caused through the deposition of monosodium urate crystals in and around synovial tissue 1.
Yoon Seok Kim +3 more
core +1 more source
Fine Needle Aspiration Cytology in the Diagnosis of Gouty Tophi - Report of Two Cases [PDF]
, 2018 Gout is a chronic hyperuricaemic crystal induced arthropathy. Tophi are soft tissue nodules, usually periarticular, that develop after long standing gouty arthritis.
Divya Radhakrishnan +4 more
core +1 more source
P022 Tophi or not tophi: that is the question [PDF]
Rheumatol Adv PractAbstract Introduction Gouty tophi and pigmented villonodular synovitis (PVNS) may both present as an isolated mass with similar imaging findings. We present a case of gout presenting as an isolated tophus in the absence of any joint inflammation.
Cox, Miriam, Umair, Hafiz
europepmc +3 more sources
ACR Open Rheumatology, Volume 8, Issue 7, July 2026.Objective Although gout is traditionally conceptualized as an episodic disease characterized by acute flares and symptom‐free intercritical periods, some individuals report persistent joint pain that extends beyond flares. This cross‐sectional analysis aimed to explore factors associated with self‐reported pain patterns (constant vs intermittent) in ...
Sarah Stewart +8 more
wiley +1 more source