Results 131 to 140 of about 1,485,493 (255)

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Konzeption und Aufbau des automatischen Textkondensierungssystems TOPIC

, 1982
Der Bericht gibt einen Überblick über das im Aufbau befindliche Volltextanalysesystem TOPIC, mit dem eine Kondensierung (Abstracting) von Fachtexten - zunächst aus dem Bereich der Bürocomputertechnik - erreicht werden soll.
Reimer, Ulrich, Hahn, Udo, Kuhlen, Rainer   +2 more
core   +1 more source

Genre and Content Transformation of a Specialized Sports Publication: A Case Study of “Athletics” (1955–2022)

Вестник Новосибирского государственного университета. Серия: история, филология
This article offers a comprehensive analysis of genre and content transformation within specialized sports print media, exemplified through a case study of Russia’s dedicated sports publication, the “Athletics” (1955–2022).
U. Yu. Eshkinina, O. N. Eshkinina
doaj   +1 more source

Unsupervised learning of generative topic saliency for person re-identification [PDF]

, 2014
(c) 2014. The copyright of this document resides with its authors. It may be distributed unchanged freely in print or electronic forms.© 2014. The copyright of this document resides with its authors.
Wang, H, Xiang, T, Gong, S
core  

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

PECULIARITIES OF THE METAPHORIC REPRESENTATION OF THE CONCEPT OF HAPPINESS IN AMERICAN POLITICAL, RELIGIOUS AND COMMON TYPES OF DISCOURSE

Вестник Кемеровского государственного университета, 2014
This paper presents the results of analysingthe metaphoric representation of the concept of HAPPINESS in three types of discourse. The author focuses on the way the discourse influences the images representing the concept.
A. S. Vashcheulova
doaj  

TOPIC II, TOPOGRAPHIC II : automatische Textkondensierung und text-orientiertes Informationsmanagement ; Projektziele, state of the art

, 1984
Mit TOPIC 11 I TOPOGRAPHIC 11 wird das Ziel verfolgt, die aus Mitteln des BMFT geförderten Arbeiten von TOPIC I (seit 1/82) und TOPOGRAPHIC I (seit 6/83) fortzuführen und mit der Bereitstellung eines Prototyps für automatische Textkondensierung und ...
Hammwöhner, Rainer, Reimer, Ulrich, Hahn, Udo, Kuhlen, Rainer, Thiel, Ulrich   +4 more
core   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source