Results 121 to 130 of about 2,130,714 (318)

User social influence analysis based on constrained nonnegative tensor factorization

open access: yesTongxin xuebao, 2016
Existing models for measuring user social influence fail to integrate both opinion and topic information.Therefore,a new constrained nonnegative tensor factorization method combining user’s opinion and the topical relevance was proposed.The method ...
Jing-jing WEI   +4 more
doaj  

Detecting Topics and Polarity From Twitter: A University Faculty Case

open access: yesIEEE Access
Social networks have become a powerful communication tool, with millions of people exchanging information, opinions, and experiences daily. Companies, organizations, and even people have turned this tool into a marketing platform to position themselves ...
Almudena Sanchez Ruiz   +3 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

TOP2LABEL: EXPLAINABLE ZERO SHOT TOPIC LABELLING USING KNOWLEDGE GRAPHS

open access: yes, 2022
We presented the first zero-shot model to generate all three types of textual labels (i.e., 1. One Word Label, 2. Sentence Label, and 3. Summary Label) for automatically generated topics. We have defined our evaluation matrix based on BERTScore, which is
Chaudhary, Akhil
core  

On the topic of topic and topic continuity

open access: yesling, 1992
PETER SCHLOBINSKI   +1 more
openaire   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Cross Validation Of Neural Network Applications For Automatic New Topic Identification

open access: yes, 2005
There are recent studies in the literature on automatic topic-shift identification in Web search engine user sessions; however most of this work applied their topic-shift identification algorithms on data logs from a single search engine.
Özmutlu, H. Cenk   +3 more
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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