Results 101 to 110 of about 988,863 (326)

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Automatic Seed Word Selection for Topic Modeling

open access: yesIEEE Access
Topic modeling is widely used to uncover latent semantic topics from a corpus. However, topic models often struggle to identify minor topics due to their tendency to prioritize dominant patterns in the data. They are also hindered by polysemous words and
Dahyun Jeong   +3 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Topic Modeling

open access: yes
Im KONDE-Projekt, das aus Hochschulraumstrukturmitteln finanziert wird, beschäftigten sich sieben universitäre Partner und drei weitere Einrichtungen aus unterschiedlichen Blickwinkeln mit theoretischen und praktischen Aspekten der Digitalen Edition. Ein Outcome des Projektes stellt das Weißbuch dar, welches über 200 Artikel zum Thema Digitale Edition ...
Yanghui Rao, Qing Li
  +5 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Research Community Mining via Generalized Topic Modeling [PDF]

open access: yesMehran University Research Journal of Engineering and Technology, 2012
Mining research community on the basis of hidden relationships present between its entities is important from academic recommendation point of view. Previous approaches discovered research community by using network connectivity based distance measures
Ali Daud   +2 more
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A Gentle Introduction to Topic Modeling Using Python

open access: yesTheological Librarianship, 2018
Topic modeling is a data mining method which can be used to understand and categorize large corpora of data; as such, it is a tool which theological librarians can use in their professional workflows and scholarly practices.
Micah D. Saxton
doaj   +1 more source

CTM - A Model for Large-Scale Multi-View Tweet Topic Classification [PDF]

open access: gold, 2022
Vivek Kulkarni   +2 more
openalex   +1 more source

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