Results 131 to 140 of about 988,863 (326)

Integration of Neural Embeddings and Probabilistic Models in Topic Modeling

open access: yesApplied Artificial Intelligence
Topic modeling, a way to find topics in large volumes of text, has grown with the help of deep learning. This paper presents two novel approaches to topic modeling by integrating embeddings derived from Bert-Topic with the multi-grain clustering topic ...
Pantea Koochemeshkian, Nizar Bouguila
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Conceptualization Topic Modeling

open access: yes, 2017
Recently, topic modeling has been widely used to discover the abstract topics in text corpora. Most of the existing topic models are based on the assumption of three-layer hierarchical Bayesian structure, i.e. each document is modeled as a probability distribution over topics, and each topic is a probability distribution over words.
Tang, Yi-Kun   +3 more
openaire   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Tree-Structured Neural Topic Model [PDF]

open access: gold, 2020
Masaru Isonuma   +3 more
openalex   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Categorizing E-cigarette-related tweets using BERT topic modeling

open access: yesEmerging Trends in Drugs, Addictions, and Health
Background: Social media platforms are critical channels for promoting e-cigarettes, particularly among youth, making analysis of their vast and diverse content essential for public health interventions.
D. Murthy   +8 more
doaj   +1 more source

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