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“There’s Not Enough Bodies to Do the Demand:” An Exploration of Key Stakeholder Views on the Role of Health Service Capacity in Shaping Cancer Outcomes in 7 International Cancer Benchmarking Partnership Countries [PDF]

International Journal of Health Policy and Management, 2022
BackgroundDifferences in cancer survival are shaped by differences in health system capacity in workforce and infrastructure. Part of the International Cancer Benchmarking Partnership (ICBP), this study explored stakeholders’ perceptions of the role of ...
Maureen Seguin, Melanie Morris, Martin McKee, Ellen Nolte   +3 more
doaj   +1 more source

Towards Optimal pH of the Skin and Topical Formulations: From the Current State of the Art to Tailored Products

Cosmetics, 2021
Acidic pH of the skin surface has been recognized as a regulating factor for the maintenance of the stratum corneum homeostasis and barrier permeability.
M. Lukić, I. Pantelić, S. Savić
semanticscholar   +1 more source

Topical Probiotics: More Than a Skin Deep

Pharmaceutics, 2022
Skin, an exterior interface of the human body is home to commensal microbiota and also acts a physical barrier that protects from invasion of foreign pathogenic microorganisms.
M. Habeebuddin, R. Karnati, P. Shiroorkar, S. Nagaraja, S. M. Asdaq, M. Khalid Anwer, S. Fattepur   +6 more
semanticscholar   +1 more source

Skin permeation and penetration of mometasone furoate in the presence of emollients: An ex vivo evaluation of clinical application protocols

Skin Health and Disease, 2023
Background Topical corticosteroids (TCS) and emollients are developed independently by the pharmaceutical industry but are often used together in practice.
Mubinah T. Beebeejaun, Marc B. Brown, Victoria Hutter, Laura Kravitz, William J. McAuley   +4 more
doaj   +1 more source

Effect and mechanism of longkui yinxiao soup in treating psoriasis in mice

Frontiers in Pharmacology, 2023
Objective: Longkui Yinxiao Soup is a traditional Chinese medicine formula used to treat psoriasis for decades. Although Longkui Yinxiao Soup showed promising efficacy in clinical practice, the regulatory mechanisms of Longkui Yinxiao Soup remain elusive.
Congcong Zhu, Congcong Zhu, Ya Chen, Ya Chen, Zongguang Tai, Zongguang Tai, Huijun Pan, Huijun Pan, Min Shen, Min Shen, Zhongjian Chen, Zhongjian Chen, Quangang Zhu, Quangang Zhu   +13 more
doaj   +1 more source

Phytosomes as an Emerging Nanotechnology Platform for the Topical Delivery of Bioactive Phytochemicals

Pharmaceutics, 2021
The emergence of phytosome nanotechnology has a potential impact in the field of drug delivery and could revolutionize the current state of topical bioactive phytochemicals delivery.
Waleed S. Alharbi, Fahad A. Almughem, Alshaimaa M Almehmady, Somayah J. Jarallah, Wijdan K Alsharif, Nouf M Alzahrani, Abdullah A. Alshehri   +6 more
semanticscholar   +1 more source

Reduced skin permeation and penetration of clobetasol propionate when Dermovate cream is applied at short time intervals with emollients

JEADV Clinical Practice, 2023
Background Dermovate cream containing 0.05% clobetasol propionate is a very potent topical corticosteroid (TCS) used in the treatment of severe inflammatory dermatoses.
M. T. Beebeejaun, M. B. Brown, V. Hutter, L. Kravitz, W. J. McAuley   +4 more
doaj   +1 more source

Combining network pharmacology, molecular docking, molecular dynamics simulation, and experimental verification to examine the efficacy and immunoregulation mechanism of FHB granules on vitiligo

Frontiers in Immunology, 2023
BackgroundFufang Honghua Buji (FHB) granules, have proven efficacy against vitiligo in long-term clinical practice. However, its major active chemical components and molecular mechanisms of action remain unknown.
Xiaolong Li, Xiaolong Li, Fengze Miao, Fengze Miao, Rujuan Xin, Rujuan Xin, Zongguang Tai, Zongguang Tai, Huijun Pan, Huijun Pan, Hao Huang, Hao Huang, Junxia Yu, Junxia Yu, Zhongjian Chen, Zhongjian Chen, Quangang Zhu, Quangang Zhu   +17 more
doaj   +1 more source

Topical-Chat: Towards Knowledge-Grounded Open-Domain Conversations [PDF]

Interspeech, 2019
Building socialbots that can have deep, engaging open-domain conversations with humans is one of the grand challenges of artificial intelligence (AI). To this end, bots need to be able to leverage world knowledge spanning several domains effectively when
Karthik Gopalakrishnan, Behnam Hedayatnia, Qinlang Chen, Anna Gottardi, Sanjeev Kwatra, Anu Venkatesh, Raefer Gabriel, Dilek Z. Hakkani-Tür   +7 more
semanticscholar   +1 more source

High Content Image Analysis as a Tool to Morphologically Distinguish Macrophage Activation and Determine Its Importance for Foamy Alveolar Macrophage Responses

Frontiers in Immunology, 2021
IntroductionLung diseases are an increasing global health burden affecting millions of people worldwide. Only a few new inhaled medicines have reached the market in the last 30 years, in part due to foamy alveolar macrophage (FAM) responses observed in ...
Ewelina Hoffman, Paulina Napieralska, Rhamiya Mahendran, Darragh Murnane, Victoria Hutter   +4 more
doaj   +1 more source