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“There’s Not Enough Bodies to Do the Demand:” An Exploration of Key Stakeholder Views on the Role of Health Service Capacity in Shaping Cancer Outcomes in 7 International Cancer Benchmarking Partnership Countries [PDF]

International Journal of Health Policy and Management, 2022
BackgroundDifferences in cancer survival are shaped by differences in health system capacity in workforce and infrastructure. Part of the International Cancer Benchmarking Partnership (ICBP), this study explored stakeholders’ perceptions of the role of ...
Maureen Seguin, Melanie Morris, Martin McKee, Ellen Nolte   +3 more
doaj   +1 more source

Skin permeation and penetration of mometasone furoate in the presence of emollients: An ex vivo evaluation of clinical application protocols

Skin Health and Disease, 2023
Background Topical corticosteroids (TCS) and emollients are developed independently by the pharmaceutical industry but are often used together in practice.
Mubinah T. Beebeejaun, Marc B. Brown, Victoria Hutter, Laura Kravitz, William J. McAuley   +4 more
doaj   +1 more source

Effect and mechanism of longkui yinxiao soup in treating psoriasis in mice

Frontiers in Pharmacology, 2023
Objective: Longkui Yinxiao Soup is a traditional Chinese medicine formula used to treat psoriasis for decades. Although Longkui Yinxiao Soup showed promising efficacy in clinical practice, the regulatory mechanisms of Longkui Yinxiao Soup remain elusive.
Congcong Zhu, Congcong Zhu, Ya Chen, Ya Chen, Zongguang Tai, Zongguang Tai, Huijun Pan, Huijun Pan, Min Shen, Min Shen, Zhongjian Chen, Zhongjian Chen, Quangang Zhu, Quangang Zhu   +13 more
doaj   +1 more source

Reduced skin permeation and penetration of clobetasol propionate when Dermovate cream is applied at short time intervals with emollients

JEADV Clinical Practice, 2023
Background Dermovate cream containing 0.05% clobetasol propionate is a very potent topical corticosteroid (TCS) used in the treatment of severe inflammatory dermatoses.
M. T. Beebeejaun, M. B. Brown, V. Hutter, L. Kravitz, W. J. McAuley   +4 more
doaj   +1 more source

Combining network pharmacology, molecular docking, molecular dynamics simulation, and experimental verification to examine the efficacy and immunoregulation mechanism of FHB granules on vitiligo

Frontiers in Immunology, 2023
BackgroundFufang Honghua Buji (FHB) granules, have proven efficacy against vitiligo in long-term clinical practice. However, its major active chemical components and molecular mechanisms of action remain unknown.
Xiaolong Li, Xiaolong Li, Fengze Miao, Fengze Miao, Rujuan Xin, Rujuan Xin, Zongguang Tai, Zongguang Tai, Huijun Pan, Huijun Pan, Hao Huang, Hao Huang, Junxia Yu, Junxia Yu, Zhongjian Chen, Zhongjian Chen, Quangang Zhu, Quangang Zhu   +17 more
doaj   +1 more source

High Content Image Analysis as a Tool to Morphologically Distinguish Macrophage Activation and Determine Its Importance for Foamy Alveolar Macrophage Responses

Frontiers in Immunology, 2021
IntroductionLung diseases are an increasing global health burden affecting millions of people worldwide. Only a few new inhaled medicines have reached the market in the last 30 years, in part due to foamy alveolar macrophage (FAM) responses observed in ...
Ewelina Hoffman, Paulina Napieralska, Rhamiya Mahendran, Darragh Murnane, Victoria Hutter   +4 more
doaj   +1 more source

Dexamethasone-Loaded Lipomers: Development, Characterization, and Skin Biodistribution Studies

Pharmaceutics, 2021
Follicular targeting has gained more attention in recent decades, due to the possibility of obtaining a depot effect in topical administration and its potential as a tool to treat hair follicle-related diseases.
Eloy Pena-Rodríguez, Maria Lajarin-Reinares, Aida Mata-Ventosa, Sandra Pérez-Torras, Francisco Fernández-Campos   +4 more
doaj   +1 more source

(a-)Topics and animacy

Glossa: a journal of general linguistics, 2021
The aim of this paper is twofold: first, we intend to contribute to the debate on the identification of the features to which syntactic locality expressed in terms of the featural Relativized Minimality/ fRM principle appears to be sensitive (Rizzi 2004; Friedmann, Belletti & Rizzi 2009); second, we aim at providing a better characterization of
Adriana Belletti, Claudia Manetti
openaire   +6 more sources

Epidermal Delivery of Retinyl Palmitate Loaded Transfersomes: Penetration and Biodistribution Studies

Pharmaceutics, 2020
The alteration of retinoids levels in the skin can cause different disorders in the maturation of epithelial skin cells. Topical administration of these lipophilic molecules is a challenge that can be addressed by encapsulation into drug delivery systems.
Eloy Pena-Rodríguez, Mari Carmen Moreno, Bárbara Blanco-Fernandez, Jordi González, Francisco Fernández-Campos   +4 more
doaj   +1 more source

Wettability and contact angle affect precorneal retention and pharmacodynamic behavior of microspheres

Drug Delivery, 2021
In the present study, we describe the development of betaxolol hydrochloride and montmorillonite with ion exchange in a single formulation to create a novel micro-interactive dual-functioning sustained-release delivery system (MIDFDS) for the treatment ...
Hanyu Liu, Xinyue Han, Huamei Li, Qi Tao, Jie Hu, Shuo Liu, Huaixin Liu, Jun Zhou, Wei Li, Fan Yang, Qineng Ping, Shijie Wei, Hongmei Liu, Huaqing Lin, Dongzhi Hou   +14 more
doaj   +1 more source