Results 11 to 20 of about 122,904 (310)

Topical ocular delivery of nanoparticles with epoetin beta in Wistar Hannover rats

open access: yesScientific Reports, 2023
Topical instillation of drugs targeting the posterior ocular segment is an expanding area of research. Chitosan and hyaluronic acid have remarkable mucoadhesive properties and potentially enhance pre-corneal retention time after topical instillation ...
Beatriz Silva   +3 more
doaj   +1 more source

Topical ophthalmic atropine in horses, pharmacokinetics and effect on intestinal motility

open access: yesBMC Veterinary Research, 2021
Background Topical ophthalmic atropine sulfate is an important part of the treatment protocol in equine uveitis. Frequent administration of topical atropine may cause decreased intestinal motility and colic in horses due to systemic exposure.
L. Ström   +7 more
doaj   +1 more source

TOPICAL NONSTEROID ANTI-INFLAMATORY DRUGS – INDICATIONS, EFFICACY AND SAFETY [PDF]

open access: yesRomanian Journal of Rheumatology, 2019
Topical Nonsteroid anti-inflammatory drugs are efficient for the treatment of acute and chronic pain in musculo-skeletal diseases. There clinical benefit is similar to the oral form of administration, but with significant less systemic adverse events ...
Diana Mazilu, Ruxandra Ionescu
doaj   +1 more source

Lipid vesicular gels for topical administration of antioxidants

open access: yesColloids and Surfaces B: Biointerfaces, 2022
The application of a formulation on the skin represents an effective way to deliver bio-active molecules for therapeutical purposes. Moreover, the outermost skin layer, the stratum corneum, can be overcome by employing chemical permeation enhancers and edge activators as components.
Fornasier, Marco   +5 more
openaire   +4 more sources

Study of bases influence on the biopharmaceutical characteristics of the pastes for onychomycosis therapy

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2018
According to the European and American authors the onychomycosis prevalence in the world has amount from 8.0 % to 26.9 %. Topical treatment of onychomycosis in most cases is the only acceptable method of therapy mainly due to high safety.
V. V. Luc   +3 more
doaj   +1 more source

Bisphosphonate: Brief Review of Its Development for Usage in Dentistry

open access: yesJournal of Dentistry Indonesia, 2013
Bisphosphonate (BP) is a class of drug that prevent the loss of bone mass. It inhibits the resorption of bone by encouraging osteoclast to undergo apoptosis.
Tita Ratya Utari
doaj   +1 more source

Systemic and topical administration of spermidine accelerates skin wound healing

open access: yesCell Communication and Signaling, 2021
Background The skin wound healing process is regulated by various cytokines, chemokines, and growth factors. Recent reports have demonstrated that spermine/spermidine (SPD) promote wound healing through urokinase-type plasminogen activator (uPA)/uPA ...
Daisuke Ito   +5 more
doaj   +1 more source

Corneal Infection Therapy with Topical Bacteriophage Administration [PDF]

open access: yesThe Open Ophthalmology Journal, 2015
Staphylococcus aureus is a major pathogen in bacterial keratitis, a vision-threatening disease. Although the incidence of S. aureus keratitis varies worldwide, the increasing trend of resistance to certain antibiotics makes this condition an important, global, healthcare concern.
Jean-Marc Legeais   +2 more
openaire   +3 more sources

Effects of Combined Intralesional 5-Fluorouracil and Topical Silicone in Prevention of Keloids: A Double Blind Randomized Clinical Trial Study [PDF]

open access: yesActa Medica Iranica, 2011
Keloids are aesthetically disfiguring and severely disabling. The optimal treatment remains undefined. This clinical study, evaluate the efficacy and side effects of combined topical silicone and 5-Fluorouracil on the prevention of keloids.
Ebrahim Hatamipour   +3 more
doaj   +1 more source

In Vivo Evaluation of Cefuroxime Axetil-Loaded Bioadhesive Nanoparticles to Treat Haemophilus influenzae-Induced Otitis Media

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Otitis media (OM) is a common disease in children. One of the most common pathogens causing OM is non-typeable Haemophilus influenzae (NTHi). NTHi in the middle ear can be successfully eradicated by a regimen of oral antibiotics sustained for 7–10 days ...
Hong Lin   +6 more
doaj   +1 more source

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