Results 11 to 20 of about 325,333 (335)

Hyaluronic acid: perspectives in upper aero-digestive tract. A systematic review [PDF]

, 2015
Background: To date, topical therapies guarantee a better delivery of high concentrations of pharmacologic agents to the mucosa of the upper aerodigestive tract (UADT).
Baptista, Peter, Casale, Manuele, Moffa, Antonio, Oliveto, Giuseppe, Pace, Annalisa, Sabatino, Lorenzo, Salvinelli, Fabrizio, Vitali, Massimiliano   +7 more
core   +10 more sources

Topical Administration of Novel FKBP12 Ligand MP-004 Improves Retinal Function and Structure in Retinitis Pigmentosa Models. [PDF]

Invest Ophthalmol Vis Sci
Lara-López A, Gonzalez-Imaz K, Rodríguez-Hidalgo M, Sarasola-Gastesi M, Escudero-Arrarás L, Milla-Navarro S, de la Villa P, Sagartzazu-Aizpurua M, Miranda JI, Aizpurua JM, de Munain AL, Vallejo-Illarramendi A, Ruiz-Ederra J.   +12 more
europepmc   +2 more sources

Topical (S)-ketamine for pain management of postherpetic neuralgia [PDF]

Anais Brasileiros de Dermatologia, 2012
Herpes zoster infection may cause postherpetic neuralgia, which is defined by prolonged pain predominantly mediated by central nervous system hypersensitivity.
Guilherme Antonio Moreira de Barros, Hélio Amante Miot, Ademir Massarico Braz, Flávia Ramos, Marcos Aristoteles Borges   +4 more
doaj   +1 more source

Topical ocular delivery of nanoparticles with epoetin beta in Wistar Hannover rats

Scientific Reports, 2023
Topical instillation of drugs targeting the posterior ocular segment is an expanding area of research. Chitosan and hyaluronic acid have remarkable mucoadhesive properties and potentially enhance pre-corneal retention time after topical instillation ...
Beatriz Silva, Lídia M. Gonçalves, Berta São Braz, Esmeralda Delgado   +3 more
doaj   +1 more source

Topical Ocular Administration of Progesterone Decreases Photoreceptor Cell Death in Retinal Degeneration Slow (rds) Mice

Pharmaceuticals, 2022
Retinitis pigmentosa (RP) is an inherited eye disorder which triggers a cascade of retinal disorders leading to photoreceptor cell death and for which there is currently no effective treatment.
Adrián M. Alambiaga-Caravaca, Antolín Cantó, Vicent Rodilla, María Miranda, Alicia López-Castellano   +4 more
doaj   +1 more source

Topical ophthalmic atropine in horses, pharmacokinetics and effect on intestinal motility

BMC Veterinary Research, 2021
Background Topical ophthalmic atropine sulfate is an important part of the treatment protocol in equine uveitis. Frequent administration of topical atropine may cause decreased intestinal motility and colic in horses due to systemic exposure.
L. Ström, F. Dalin, M. Domberg, C. Stenlund, U. Bondesson, M. Hedeland, P-L Toutain, C. Ekstrand   +7 more
doaj   +1 more source

TOPICAL NONSTEROID ANTI-INFLAMATORY DRUGS – INDICATIONS, EFFICACY AND SAFETY [PDF]

Romanian Journal of Rheumatology, 2019
Topical Nonsteroid anti-inflammatory drugs are efficient for the treatment of acute and chronic pain in musculo-skeletal diseases. There clinical benefit is similar to the oral form of administration, but with significant less systemic adverse events ...
Diana Mazilu, Ruxandra Ionescu
doaj   +1 more source

Study of bases influence on the biopharmaceutical characteristics of the pastes for onychomycosis therapy

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2018
According to the European and American authors the onychomycosis prevalence in the world has amount from 8.0 % to 26.9 %. Topical treatment of onychomycosis in most cases is the only acceptable method of therapy mainly due to high safety.
V. V. Luc, V. V. Gladyshev, A.P. Lisyanskaya, A.D. Diudiun   +3 more
doaj   +1 more source

3-hydroxykynurenine suppresses CD4+ T-cell proliferation, induces T-regulatory-cell development, and prolongs corneal allograft survival [PDF]

, 2011
Copyright © 2011 Association for Research in Vision and Ophthalmology. This article is available open access through the publisher’s website at the link below.Purpose.
Fu, Hongmei, George, Andrew J. T., Germain, Conrad, Larkin, Daniel F. P., Zaher, Sarah S.   +4 more
core   +2 more sources

Systemic and topical administration of spermidine accelerates skin wound healing

Cell Communication and Signaling, 2021
Background The skin wound healing process is regulated by various cytokines, chemokines, and growth factors. Recent reports have demonstrated that spermine/spermidine (SPD) promote wound healing through urokinase-type plasminogen activator (uPA)/uPA ...
Daisuke Ito, Hiroyasu Ito, Takayasu Ideta, Ayumu Kanbe, Soranobu Ninomiya, Masahito Shimizu   +5 more
doaj   +1 more source