Results 41 to 50 of about 2,598,787 (372)

Topical Administration of Terpenes Encapsulated in Nanostructured Lipid-Based Systems

Molecules, 2020
Terpenes are a group of phytocompounds that have been used in medicine for decades owing to their significant role in human health. So far, they have been examined for therapeutic purposes as antibacterial, anti-inflammatory, antitumoral agents, and the ...
E. Lasoń
semanticscholar   +1 more source

Topical administration of the kappa opioid receptor agonist nalfurafine suppresses corneal neovascularization and inflammation

Scientific Reports, 2020
Corneal neovascularization (CNV) causes higher-order aberrations, corneal edema, ocular inflammation, and corneal transplant rejection, thereby decreasing visual acuity.
Hurramhon Shokirova, Takenori Inomata, Tsuyoshi Saitoh, Jun Zhu, Kenta Fujio, Yuichi Okumura, Ai Yanagawa, K. Fujimoto, Jaemyoung Sung, A. Eguchi, Maria Miura, K. Nagino, Kunihiko Hirosawa, Mizu Kuwahara, Yasutsugu Akasaki, H. Nagase, A. Murakami   +16 more
semanticscholar   +1 more source

A Novel Model of Pain Sensation Using Superfused Gastrosplenic Omentum Preparation of Anesthetized Rats

Journal of Pharmacological Sciences, 2008
A pain model for screening analgesics was established in anesthetized rats. The omenta of urethane-anesthetized rats were exteriorized, fixed in a plastic chamber, and superfused with Tyrode solution.
Shi-Jie Yang, Makoto Katori, Masataka Majima   +2 more
doaj   +1 more source

Graphene Oxide Topical Administration: Skin Permeability Studies [PDF]

Materials, 2021
Nanostructured carriers have been widely used in pharmaceutical formulations for dermatological treatment. They offer targeted drug delivery, sustained release, improved biostability, and low toxicity, usually presenting advantages over conventional formulations. Due to its large surface area, small size and photothermal properties, graphene oxide (GO)
Filipa A. L. S. Silva, Raquel Costa-Almeida, Licínia Timochenco, Sara I. Amaral, Soraia Pinto, Inês C. Gonçalves, José R. Fernandes, Fernão D. Magalhães, Bruno Sarmento, Artur M. Pinto   +9 more
openaire   +4 more sources

Plasma pharmacokinetics of tigolaner, emodepside, and praziquantel following topical administration of a combination product (Felpreva®) and of intravenous administration of the individual active ingredients in cats

Current Research in Parasitology and Vector-Borne Diseases, 2023
Felpreva® for cats contains the new acaricidal/insecticidal active ingredient tigolaner in a fixed combination with the nematocidal and cestocidal compounds emodepside and praziquantel, respectively.
Norbert Mencke, Wolfgang Bäumer, Kristine Fraatz, Ralph Krebber, Marc Schneider, Katrin Blazejak   +5 more
doaj   +1 more source

Ice versus lidocaine 5% gel for topical anaesthesia of oral mucosa – a randomized cross-over study

BMC Anesthesiology, 2019
Background Topical anaesthesia is important to optimize pain control during dental injection. Our aim was to describe a new simple method for topical anaesthesia of oral mucosa and to compare the effectiveness of ice and lidocaine 5% gel for topical ...
Nishma Hindocha, Filip Manhem, Emmanuel Bäckryd, Mats Bågesund   +3 more
doaj   +1 more source

Novel locally active estrogens accelerate cutaneous wound healing-part 2 [PDF]

, 2017
Estrogen deprivation is associated with delayed healing, while estrogen replacement therapy (ERT) accelerates acute wound healing and protects against development of chronic wounds.
Bartoli, Gabriele, Bella, Angela La, Brufani, Mario, Ceccacci, Francesca, Ciana, Paolo, D’Aiuto, Virginia, FILOCAMO, Luigi, LEONELLI, Francesca, Maggi, Adriana, MARINI BETTOLO, Rinaldo, Meda, Clara, MIGNECO, Luisa Maria, Rizzi, Nicoletta   +12 more
core   +2 more sources

New patents on topical anesthetics. [PDF]

, 2014
Anesthesia is defined as a total or partial loss of sensation and it may be general, local or topical, depending on the method of drug administration and area of the body affected.
CALVIERI, Stefano, CANTISANI, CARMEN, D'ANDREA, Vito, Frascani, F, MACALUSO, LAURA, paolino, giovanni, RICHETTA, Antonio Giovanni   +6 more
core   +1 more source

Topical treatment of peripheral neuropathic pain: applying the evidence [PDF]

, 2017
Patients with peripheral neuropathic pain (NP) may only achieve partial pain relief with currently recommended first-line oral treatments, which are also associated with systemic adverse events.
Cruccu, Giorgio, Sommer, Claudia
core   +1 more source

Nanocarriers for topical administration of resveratrol: A comparative study

International Journal of Pharmaceutics, 2013
The trans-resveratrol (t-res), a non-flavonoid polyphenol extracted from different plants, has recently earned interest for application on the skin for different applications. In this work, the potential of nanocarriers, namely transfersomes and ethanol-containing vesicles, to deliver t-res into/through the skin was investigated.
SCOGNAMIGLIO, IMMACOLATA, DE STEFANO, DANIELA, CAMPANI, VIRGINIA, MAYOL, LAURA, CARNUCCIO, ROSA, FABBROCINI, GABRIELLA, AYALA, FABIO, La Rotonda MI, DE ROSA, GIUSEPPE   +8 more
openaire   +3 more sources