Results 111 to 120 of about 30,582 (303)

Comparison of efficacy of photobiomodulation and topical anesthetic spray in reducing the injection pain in children aged 6–12 years – A randomized clinical trial

open access: yesJournal of Indian Society of Pedodontics and Preventive Dentistry
Background: Local anesthesia administration is associated with pain, resulting in dental anxiety in children. Various techniques have been tried to minimize this discomfort such as topical anesthetic gel, spray, Vibration of tissue, and distraction ...
Bhavana Bollepalli   +5 more
doaj   +1 more source

Evaluation of aerosolized medications during parabolic flight maneuvers [PDF]

open access: yes
The goal was to visually evaluate the effect gravity has on delivery of medications by the use of various aerosol devices. During parabolic flight the same four aerosols were retested as performed in studio ground tests.
Gosbee, John   +2 more
core   +1 more source

Comparison of Injection Discomfort and Anesthetic Duration of Plain Polocaine versus Epinephrine containing Articaine and Lidocaine [PDF]

open access: yes, 2013
Purpose: To determine possible differences in the pain level and soft tissue anesthesia duration of plain polocaine versus epinephrine-containing articaine and lidocaine during intraoral injections.
Doan, Dana
core   +1 more source

Erasable FAP Targeted Spray‐On Probe for Fluorescence‐Guided Surgery

open access: yesAdvanced Science, EarlyView.
We present the first erasable spray‐on probe for fluorescence‐guided surgery. Following topical delivery, FAP‐FLASH550 targets fibroblast activation protein–expressing stromal cells, delineating tumor margins with high tumor‐to‐background ratios. A 365 nm UV light pulse rapidly erases fluorescent signals through triazene photodegradation and subsequent
Zachary Rabinowitz   +2 more
wiley   +1 more source

Tracking of [14C]Polystyrene Nanoplastics in Pregnant Mice

open access: yesAdvanced Science, EarlyView.
This study investigates [14C]polystyrene nanoplastic ([14C]PS) translocation in late‐stage pregnant mice after intranasal (0.5 mg of [14C]PS on GD12, GD14, and GD16, n = 6) and intravenous administration (1.5 mg of [14C]PS on GD16, n = 6). 14C‐radiolabel allows quantitative tracking of unmodified polystyrene nanoplastics.
Olga Khaybullina   +2 more
wiley   +1 more source

Deciphering the Impact of RAC1‐SPTAN1 in ARPKD Cystogenesis Using Multifaceted Models

open access: yesAdvanced Science, EarlyView.
Distal/connecting tubules expressing SLC8A1 have been suggested as a potential origin of ARPKD cysts. SPTAN1 has been identified as a key molecule in ARPKD cyst formation. Restoring SPTAN1 in PKHD1−/− organoids reduced cyst formation, normalized calcium levels, and decreased RAC1/c‐FOS expression, highlighting SPTAN1's role in ARPKD and the potential ...
Shohei Kuraoka   +9 more
wiley   +1 more source

Comparison the Pain Relief of Amitriptyline Mouthwash with Benzydamine in Oral Mucositis

open access: yesJournal of Dentistry, 2018
Statement of the Problem: A significant proportion of patients undergoing chemotherapy or radiotherapy suffer from mucositis. The first symptom of oral mucositis is pain. Severe pain, burning sensation, and discomfort in the oral cavity make it difficult
Shahla Kakoei   +5 more
doaj  

Laparoscopic Delivery of a MnO2‐P‐ICG Patch for Photodynamic Therapy and NK Cell‐Driven Immunotherapy in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
This study proposes a flexible MnO2‐P‐ICG nanofiber patch for laparoscopic treatment of liver tumors. The patch alleviates tumor hypoxia and induces photodynamic therapy (PDT) triggered immunogenic cell death, thereby activating the cGAS‐STING pathway and, in synergy with pachymaran, promoting NK cell–mediated innate immunity. This synergistic strategy
Jie Lin   +14 more
wiley   +1 more source

Safety, efficacy, and patient acceptability of lidocaine hydrochloride ophthalmic gel as a topical ocular anesthetic for use in ophthalmic procedures

open access: yesClinical Ophthalmology, 2009
Michael A Page, Frederick W FraunfelderDepartment of Ophthalmology (Casey Eye Institute), Oregon Health and Science University, Portland, OR, USAPurpose: To review the current literature on safety, efficacy, and measures of surgeon and patient ...
Michael A Page   +1 more
doaj  

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