Results 101 to 110 of about 19,485 (207)

The real‐world relationship between naltrexone/bupropion treatment and weight loss in Canada: A retrospective chart review

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary This study examined the change in weight at 6 months of naltrexone/bupropion (NB), a combination pharmacological therapy for weight management, in real‐world practice in Canada. The study was conducted through an observational, retrospective, single‐arm chart review of adult patients who attended the Wharton Medical Clinic in Ontario, Canada ...
Sean Wharton, Elham Kamran, Lehana Thabane, Peter Yin, Rebecca Christensen   +4 more
wiley   +1 more source

Comprehensive review of visual defects reported with topiramate

Clinical Ophthalmology, 2017
Lisa Ford,1 Jeffrey L Goldberg,2 Fred Selan,1 Howard E Greenberg,1 Yingqi Shi1 1Janssen Research & Development, LLC, Titusville, NJ, 2Byers Eye Institute, Stanford University, Palo Alto, CA, USA Objective: The objective of this study was to analyze
Ford L, Goldberg JL, Selan F, Greenberg HE, Shi Y   +4 more
doaj  

Intravenous immunoglobulin and febrile status epilepticus in children with Dravet syndrome: A retrospective multicentre study

Developmental Medicine &Child Neurology, EarlyView.
This multicenter retrospective study evaluated the use of intravenous immunoglobulin (IVIG) in 14 children with Dravet syndrome as a preventive strategy against febrile status epilepticus. Over a 6‐month period, IVIG was associated with a significant reduction in hospitalizations for febrile status epilepticus.
Romane Marc, Nicole Chemaly, Mathieu Kuchenbuch, Caroline Espil‐Taris, Elodie Lametery, Hélène Maurey, Sylviane Peudenier, Sylvie Nguyen The Tich, Rima Nabbout, Claire Bar   +9 more
wiley   +1 more source

Seizures in children with Dravet syndrome in extreme heat: A qualitative study of parental perspectives

Developmental Medicine &Child Neurology, EarlyView.
Perspectives of parents of children with Dravet syndrome indicate that extreme heat and high temperatures exacerbate epileptic seizures, introduce new seizure triggers, and require the adoption of specific seizure‑management strategies. Abstract Aim To describe parental perspectives on how heatwaves and high ambient temperatures influence seizure ...
Angel Aledo‐Serrano, José Ángel Aibar, Domingo Palacios‐Ceña, Maria Salcedo‐Perez‐Juana, Maria Palacios‐Ceña, Simona Giorgi, Manuel Lorenzo‐Dieguez, Sanjay M Sisodiya, Cristina García‐Bravo   +8 more
wiley   +1 more source

Sodium‐glucose co‐transporter 2 inhibitors and obesity‐associated cancers in people with type 2 diabetes: A real‐world observational study

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims To investigate the association between sodium‐glucose co‐transporter 2 inhibitors (SGLT‐2i) and obesity‐associated cancers (OAC) in individuals with type 2 diabetes (T2D). Materials and Methods This retrospective cohort study used data from the TriNetX US Collaborative Network.
Testimony Ipaye, Jonathan Goldney, Thomas Yates, Francesco Zaccardi, Kamlesh Khunti, Elina Akalestou, Melanie J. Davies, Karen Brown, Dimitris Papamargaritis   +8 more
wiley   +1 more source

Topiramate‐induced acute angle closure with suprachoroidal effusion: Insights from a novel ultra‐wide‐field OCT device

Acta Ophthalmologica, EarlyView.
Michael Hafner, Nicolas Pensel, Nicolas C. D. Scherer, Marc J. Mackert, Siegfried G. Priglinger, Leonie F. Keidel, Maximilian J. Gerhardt   +6 more
wiley   +1 more source

Obesity Treatments and Weight Changes in Clinical Practice After Discontinuation of Semaglutide or Tirzepatide

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To describe obesity treatments in real‐world settings after discontinuation of semaglutide or tirzepatide and variability in weight change post‐discontinuation. Materials and Methods This retrospective cohort study used electronic health records from 1 January 2021, to 30 June 2025, in a large health system in Ohio and Florida.
Hamlet Gasoyan, Rebecca Schulte, Christopher B. Boyer, Nicholas J. Casacchia, W. Scott Butsch, Phuc Le, Ali Aminian, Marcio L. Griebeler, Bartolome Burguera, Michael B. Rothberg   +9 more
wiley   +1 more source

Impact of long‐term treatment with cenobamate on concomitant usage of antiseizure medications: A real‐world retrospective study in Spain

Epilepsia, EarlyView.
Abstract Objectives This study explored the safety and effectiveness of adjunctive cenobamate (CNB) in patients with different levels of drug‐resistant epilepsy (DRE) in a real‐world setting, including its impact on the use of co‐antiseizure medication (co‐ASM). Methods This was a single‐center, retrospective, observational study.
Juan María Sánchez‐Caro, Roshan Hariramani Ramchandani, Iratxe Maestro Saiz, Juan Jesús Rodríguez Uranga   +3 more
wiley   +1 more source

Clinical trajectories and medication response in TBC1D24‐related epilepsies

Epilepsia, EarlyView.
Abstract Objective Biallelic variants in TBC1D24 represent a rare cause of epilepsy and neurodevelopmental disorders, including severe developmental and epileptic encephalopathies. Here, we present the first attempt to delineate the longitudinal disease histories and effectiveness of antiseizure medications (ASMs) in TBC1D24‐related disorders.
Ealing Mondragon, Jan H. Magielski, Bintou Bane, JoeyLynn Nolan, Sarah M. Ruggiero, Dallas Armstrong, Susan Arnold, Deepa Sirsi, Ingo Helbig, Jillian L. McKee   +9 more
wiley   +1 more source

Ocular changes in patients on Topiramate therapy: a hospital-based comparative study. [PDF]

BMC Ophthalmol
Patro M, Mishra S, Pattnaik S, Panigrahi PK.   +3 more
europepmc   +1 more source