Results 151 to 160 of about 29,245 (221)

Antibody-Drug Conjugates Beyond HER2 in Non-Small Cell Lung Cancer (NSCLC): Mechanisms, Emerging Targets, and Future Directions. [PDF]

Biomolecules
Ismail A, Desai A, Simon GR, Boumber Y.
europepmc   +1 more source

A high-throughput fluorescent DNA cleavage assay for discovering bacterial DNA gyrase poisons. [PDF]

Nucleic Acids Res
Dias M, Annamalai T, Otsuka Y, Leng S, Chapagain T, Ferdous S, Shumate J, Scampavia L, Spicer TP, Leng F.   +9 more
europepmc   +1 more source

Novel <i>N</i>-4-(5-Amino-7-substituted-triazolotriazinepiperazin-1-yl) Norfloxacin Analogues Exhibit Potent and Selective Anticancer Activity via Topoisomerase Inhibition, Cell-Cycle Arrest, and Apoptosis in A 431 Skin Carcinoma Cells. [PDF]

Pharmaceuticals (Basel)
El-Saghier AM, Hamed AM, Abosella L, Bräse S, Aziz HA.   +4 more
europepmc   +1 more source

Evolution and recent advances in antibody-drug conjugate therapy for lung cancer: a comprehensive systematic review based on the Trialtrove database (inception to July 1, 2025). [PDF]

Front Oncol
Chen Y, Zhang Y, Tian C, Li Z, Guo G.
europepmc   +1 more source

Discovery of potent bisindole-based pyrazolopyridine derivatives as topoisomerase inhibitors: DNA damage induction and synergistic antileukemic activity. [PDF]

Front Pharmacol
Eldehna WM, Tawfik HO, Veselá D, Peřina M, Negmeldin AT, Elsayed ZM, Majrashi TA, Vojáčková V, Elbadawi MM, Shaldam MA, Kryštof V, Abdel-Aziz HA.   +11 more
europepmc   +1 more source

Cellular strategies for repairing trapped protein-DNA complexes. [PDF]

Front Pharmacol
Sideridou M, Machli DI, Lontra D, Rampias T.   +3 more
europepmc   +1 more source

In silico evaluation of garlic-derived organosulfur compounds as multi-target inhibitors of breast cancer biomarkers. [PDF]

PLoS One
Siame C, Ofori B, Paemka L, Danquah KO.
europepmc   +1 more source

Topoisomerases as Targets for Novel Drug Discovery. [PDF]

Pharmaceuticals (Basel)
Perdih A.
europepmc   +1 more source

Amonafide Targeting NTSR1-PI3K/AKT/mTOR Signaling Attenuates Vascular Remodeling in Pulmonary Arterial Hypertension. [PDF]

J Am Heart Assoc
Zhu YJ, Kou JJ, Bo YC, Zhang MJ, Fan X, Zhao LL, Yan Y, Zhang HD, Wu WH, Yuan P, Liu Y, Shi JZ, Pang XB, He YY.   +13 more
europepmc   +1 more source

Total body irradiation and smoking interact to increase lung cancer risk after blood or marrow transplantation. [PDF]

Blood Adv
Balas N, Chen Y, Meng Q, Hageman L, Landier W, Richman J, Bosworth A, Wong FL, Bhatia R, Weisdorf DJ, Armenian SH, Bhatia S.   +11 more
europepmc   +1 more source