Results 91 to 100 of about 63,915 (257)

Parallel Genome‐Wide CRISPR Screens Reveal SORL1 and ZFYVE19 as Sequential Host Determinants of Salmonella Infection

open access: yesAdvanced Science, EarlyView.
To distinguish how Salmonella invades cells vs how it survives long‐term, a parallel CRISPR screening platform is developed. This approach reveals the host proteins that the bacterium exploits at different stages of infection. The study identifies SORL1 as a novel host factor for invasion and demonstrates that blocking it with an antibody effectively ...
Sehee Yun   +6 more
wiley   +1 more source

Khovanov-Rozansky Homology and Topological Strings [PDF]

open access: yes, 2004
We conjecture a relation between the sl(N) knot homology, recently introduced by Khovanov and Rozansky, and the spectrum of BPS states captured by open topological strings.
A. Kapustin   +22 more
core   +5 more sources

Machine Learning for Green Solvents: Assessment, Selection and Substitution

open access: yesAdvanced Science, EarlyView.
Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta   +4 more
wiley   +1 more source

Resonances and PT symmetry in quantum curves

open access: yesJournal of High Energy Physics, 2020
In the correspondence between spectral problems and topological strings, it is natural to consider complex values for the string theory moduli. In the spectral theory side, this corresponds to non-Hermitian quantum curves with complex spectra and ...
Yoan Emery   +2 more
doaj   +1 more source

Jacobi sigma models

open access: yesJournal of High Energy Physics, 2021
We introduce a two-dimensional sigma model associated with a Jacobi manifold. The model is a generalisation of a Poisson sigma model providing a topological open string theory.
Francesco Bascone   +2 more
doaj   +1 more source

Loop Variables for a Class of Conical Spacetimes [PDF]

open access: yes, 1995
Loop variables are used to describe the presence of topological defects in spacetime. In particular we study the dependence of the holonomy transformation on angular momentum and torsion for a multi-chiral cone.
P. S. Letelier   +2 more
core   +2 more sources

Cap products in string topology [PDF]

open access: yesAlgebraic & Geometric Topology, 2009
Chas and Sullivan showed that the homology of the free loop space LM of an oriented closed smooth finite dimensional manifold M admits the structure of a Batalin-Vilkovisky (BV) algebra equipped with an associative product called the loop product and a Lie bracket called the loop bracket.
openaire   +4 more sources

“Topological” formulation of effective vortex strings [PDF]

open access: yesNuclear Physics B, 1995
31page, LaTeX, 8 uuencoded epsf figures, KUNS ...
Sato, Masatoshi, Yahikozawa, Shigeaki
openaire   +3 more sources

Multi‐View Biomedical Foundation Models for Molecule‐Target and Property Prediction

open access: yesAdvanced Science, EarlyView.
Molecular foundation models can provide accurate predictions for a large set of downstream tasks. We develop MMELON, an approach that integrates pre‐trained graph, image, and text foundation models and validate our multi‐view model on over 120 tasks, including GPCR binding.
Parthasarathy Suryanarayanan   +17 more
wiley   +1 more source

A CMB Millikan experiment with cosmic axiverse strings

open access: yesJournal of High Energy Physics, 2020
We study axion strings of hyperlight axions coupled to photons. Hyperlight axions — axions lighter than Hubble at recombination — are a generic prediction of the string axiverse.
Prateek Agrawal, Anson Hook, Junwu Huang
doaj   +1 more source

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