Results 91 to 100 of about 411,480 (264)
Advanced Science, EarlyView.Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang +16 more
wiley +1 more source
Quantum mirror curve of periodic chain geometry
Journal of High Energy Physics, 2019 The mirror curves enable us to study B-model topological strings on noncompact toric Calabi-Yau threefolds. One of the method to obtain the mirror curves is to calculate the partition function of the topological string with a single brane. In this paper,
Taro Kimura, Yuji Sugimoto
doaj +1 more source
Geometrically Encoded Positioning of Introns, Intergenic Segments, and Exons in the Human Genome
Advanced Science, EarlyView.This study introduces a new hypothesis: exons, introns, and intergenic segments are non‐random projections of the functional layers of 3D structure of chromatin packing domains. Evidence is presented that this “geometric code” may encode volumetric structure, reconciling epigenetic patterns, correlates with oncogenic mutations, acting as a potential ...
Luay M. Almassalha +11 more
wiley +1 more source
Selection rules of topological solitons from non-invertible symmetries in axion electrodynamics
Journal of High Energy PhysicsWe investigate a relation between non-invertible symmetries and selection rules of topological solitons such as axionic domain walls and magnetic strings in the (3 + 1)-dimensional axion electrodynamics with a massive axion or a massive photon.
Yoshimasa Hidaka +2 more
doaj +1 more source
Quantum periods and TBA-like equations for a class of Calabi-Yau geometries
Journal of High Energy Physics, 2021 We continue the study of a novel relation between quantum periods and TBA(Thermodynamic Bethe Ansatz)-like difference equations, generalize previous works to a large class of Calabi-Yau geometries described by three-term quantum operators.
Bao-ning Du, Min-xin Huang
doaj +1 more source
Bethe/Gauge correspondence in odd dimension: modular double, non-perturbative corrections and open topological strings [PDF]
, 2016 A bstractBethe/Gauge correspondence as it is usually stated is ill-defined in five dimensions and needs a “non-perturbative” completion; a related problem also appears in three dimensions.
A. Sciarappa
semanticscholar +1 more source
Advanced Science, EarlyView.To distinguish how Salmonella invades cells vs how it survives long‐term, a parallel CRISPR screening platform is developed. This approach reveals the host proteins that the bacterium exploits at different stages of infection. The study identifies SORL1 as a novel host factor for invasion and demonstrates that blocking it with an antibody effectively ...
Sehee Yun +6 more
wiley +1 more source
Journal of High Energy PhysicsWe consider coupled gravitational and electromagnetic perturbations of a family of five-dimensional Einstein-Maxwell solutions that describes both magnetized black strings and horizonless topological stars.
Iosif Bena +3 more
doaj +1 more source
Advanced Science, EarlyView.A biomimetic nanoplatform (CeAst@MK) is engineered for precise therapy of acute kidney injury by integrating cerium‐based antioxidation, natural flavonoid astragalin, and macrophage membrane camouflage. Featuring kidney‐targeted and pH‐responsive release, CeAst@MK scavenges ROS, suppresses inflammation, and restores renal function via modulation of ...
Shichao Zhang +9 more
wiley +1 more source