Results 91 to 100 of about 63,806 (262)

Revisiting Target‐Aware de novo Molecular Generation with TarPass: Between Rational Design and Texas Sharpshooter

open access: yesAdvanced Science, EarlyView.
TarPass provides a rigorous benchmark for target‐aware de novo molecular generation by jointly evaluating protein‐ligand interactions, molecular plausibility, and drug‐likeness on 18 well‐studied targets. Results show that current models often fail to consistently surpass random baseline in target‐specific enrichment, while post hoc multi‐tier virtual ...
Rui Qin   +11 more
wiley   +1 more source

Resonances and PT symmetry in quantum curves

open access: yesJournal of High Energy Physics, 2020
In the correspondence between spectral problems and topological strings, it is natural to consider complex values for the string theory moduli. In the spectral theory side, this corresponds to non-Hermitian quantum curves with complex spectra and ...
Yoan Emery   +2 more
doaj   +1 more source

Preparation, Component Identification, and Antioxidant Activity of Anthocyanins From Punica granatum “Tunisia”

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
The preparation for Tunisian pomegranate anthocyanin extract. The molecular mechanisms underlying the antioxidant effects of these compounds were investigated using network pharmacology and molecular docking. Antioxidant activity was evaluated through DPPH, ABTS, and FRAP assays, whereas the effects on oxidative stress and inflammation were examined in
Jing Zhang   +6 more
wiley   +1 more source

Astrophysical Bounds on Global Strings [PDF]

open access: yes, 1997
Global topological defects produce nonzero stress-energy throughout spacetime, and as a result can have observable gravitational influence on surrounding matter.
A. G. Cohen   +19 more
core   +3 more sources

A CMB Millikan experiment with cosmic axiverse strings

open access: yesJournal of High Energy Physics, 2020
We study axion strings of hyperlight axions coupled to photons. Hyperlight axions — axions lighter than Hubble at recombination — are a generic prediction of the string axiverse.
Prateek Agrawal, Anson Hook, Junwu Huang
doaj   +1 more source

Quantum periods and TBA-like equations for a class of Calabi-Yau geometries

open access: yesJournal of High Energy Physics, 2021
We continue the study of a novel relation between quantum periods and TBA(Thermodynamic Bethe Ansatz)-like difference equations, generalize previous works to a large class of Calabi-Yau geometries described by three-term quantum operators.
Bao-ning Du, Min-xin Huang
doaj   +1 more source

Semi-superfluid strings in High Density QCD

open access: yes, 2005
We show that topological superfluid strings/vortices with flux tubes exist in the color-flavor locked (CFL) phase of color superconductors. Using a Ginzburg-Landau free energy we find the configurations of these strings. These strings can form during the
A. P. Balachandran   +6 more
core   +1 more source

Decoding Tattoo and Permanent Makeup Pigments: Linking Physicochemical Properties to Absorption, Distribution, Metabolism, and Elimination Profiles Using Quantitative Structure–Activity Relationship (QSAR)‐Based New Approach Methodologies (NAMs)

open access: yesAdvanced Intelligent Discovery, EarlyView.
This study applies QSAR‐based new approach methodologies to 90 synthetic tattoo and permanent makeup pigments, revealing systemic links between their physicochemical properties and absorption, distribution, metabolism, and elimination profiles. The correlation‐driven analysis using SwissADME, ChemBCPP, and principal component analysis uncovers insights
Girija Bansod   +10 more
wiley   +1 more source

Blowup equations for refined topological strings

open access: yesJournal of High Energy Physics, 2018
Göttsche-Nakajima-Yoshioka K-theoretic blowup equations characterize the Nekrasov partition function of five dimensional N = 1 $$ \mathcal{N}=1 $$ supersymmetric gauge theories compactified on a circle, which via geometric engineering correspond to the ...
Min-xin Huang, Kaiwen Sun, Xin Wang
doaj   +1 more source

Topological Strings and Quantum Spectral Problems [PDF]

open access: yes, 2014
We consider certain quantum spectral problems appearing in the study of local Calabi-Yau geometries. The quantum spectrum can be computed by the Bohr-Sommerfeld quantization condition for a period integral.
Huang, Min-xin, Wang, Xian-fu
core   +2 more sources

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