Results 111 to 120 of about 63,915 (257)

B-strings on non-Kählerian manifolds

Nuclear Physics B, 2016
We explain how to couple topological B-models whose targets are non-Kählerian manifolds to topological gravity and to thus define corresponding topological strings.
Camillo Imbimbo
doaj   +1 more source

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

Advanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng, Sharon Ai Er Lam, Wei Chun Lim, Hannah Hui Min Toh, Shi Jun Ang   +4 more
wiley   +1 more source

Topological Phase Transition in a One-Dimensional Elastic String System

Crystals, 2019
We show that topological interface mode can emerge in a one-dimensional elastic string system which consists of two periodic strings with different band topologies.
Ya-Wen Tsai, Yao-Ting Wang, Pi-Gang Luan, Ta-Jen Yen   +3 more
doaj   +1 more source

Little String Theory and Heterotic/Type II Duality

, 2003
Little String Theory (LST) is a still somewhat mysterious theory that describes the dynamics near a certain class of time-like singularities in string theory.
Abe, Abe, Abe, Aharony, Aharony, Aharony, Aharony, Aharony, Alexandrov, Antoniadis, Antoniadis, Bachas, Balasubramanian, Balasubramanian, Banin, Bartomeu Fiol, Berkovits, Berkovits, Bershadsky, Bischoff, Buchbinder, Buchbinder, Callan, Cheung, Corley, Corley, Dabholkar, David A Sahakyan, David Kutasov, de Wit, Di Francesco, Dijkgraaf, Dine, Dorn, Douglas, Elitzur, Ellis, Fateev, Fateev, Gava, Giveon, Giveon, Giveon, Giveon, Giveon, Gluck, Gluck, Gonzalez-Rey, Gopakumar, Gopakumar, Gubser, Harvey, Henningson, Hori, Hori, Hull, Junemann, Kiritsis, Kiritsis, Klebanov, Klebanov, Kounnas, Kutasov, Kutasov, Kutasov, Lechtenfeld, Lerche, Lindstrom, Lowe, Maldacena, Maldacena, Maldacena, Maldacena, Marcus, Martinec, McGreevy, McGreevy, Nappi, Ofer Aharony, Ooguri, Ooguri, Ooguri, Parnachev, Polchinski, Qiu, Sen, Stieberger, Strominger, Takayanagi, Teschner, Teschner, Tong, Vafa, Witten, Witten, Witten, Zamolodchikov, Zamolodchikov   +97 more
core   +4 more sources

Quantitative proteomics identifies clusterin as a novel biomarker for atherosclerosis

Animal Models and Experimental Medicine, EarlyView.
This schematic illustrates the proposed mechanism. In advanced atherosclerotic lesions, upregulated CLU on the cell surface activates low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1). This interaction triggers the phosphorylation and activation of AKT.
Dengfeng Ding, Yingjie Zhang, Li Zhang, Xinou Zheng, Miaomiao Niu, Yunxiao Jia, Xuezhuang Li, Hua Chen, Chao Guo, Tao Jiang, Yuqiong Zhao   +10 more
wiley   +1 more source

Topology of strings: Median string is NP-complete

Theoretical Computer Science, 2000
Given a set of strings, the problem of finding a string that minimises its distance to the set is directly related with problems frequently encountered in areas involving pattern recognition or computational biology. Based on the Levenshtein (or edit) distance, different definitions of distances between a string and a set of strings can be adopted.
de la Higuera, C., Casacuberta, F.
openaire   +1 more source

Hydrogen Bond Network‐Enhanced Zincophilic Hydroxypropyl Cellulose Hybrid Layer for an Ultra‐Stable Zinc Metal Anode

Carbon Energy, EarlyView.
The dynamic instability of the ZMA/electrolyte interface has been addressed by constructing a zincophilic hydroxypropyl cellulose hybrid layer (HZ@Zn) reinforced with hydrogen‐bonded networks on the zinc anode. This advantageous HZ@Zn not only improves ion transport kinetics but also shows lower desolvation activation energy during plating processes ...
Yi Huang, Zhenjie Liu, Chuang Jiang, Qingxi Hou, Wei Liu, Zhe Hu, Bowen Cheng   +6 more
wiley   +1 more source

String topology for Lie groups [PDF]

Journal of Topology, 2010
In 1999 Chas and Sullivan showed that the homology of the free loop space of an oriented manifold admits the structure of a Batalin-Vilkovisky algebra. In this paper we give a direct description of this Batalin-Vilkovisky algebra in the case that the manifold is a compact Lie group G. Our answer is phrased in terms of the homology of G, the homology of
openaire   +4 more sources

Nutritional Value and Memory‐Improving Effects of Seven Major Nuts: A Comprehensive Study Using Network Pharmacology and In Vivo Assays

Food Frontiers, EarlyView.
This study highlights the memory‐enhancing effects of walnuts, almonds, and Torreya, with walnuts showing the strongest potential to improve cognitive function and delay brain aging. ABSTRACT This study explored the memory‐enhancing potential of seven commercially available nuts through nutritional profiling, metabolomics, network pharmacology, and ...
Jiamin Chen, Ben Niu, Ruiling Liu, Chaoyi Shen, Huizhi Chen, Mohamed A. Farag, Hangjun Chen, Qi Chen, Long Jin, Weijie Wu, Haiyan Gao   +10 more
wiley   +1 more source

Topological structures, dark matter and gravitational waves in E6

Journal of High Energy Physics
We discuss the appearance of topological structures from the spontaneous breaking of E 6 to the Standard Model via its maximal subgroup SO(10) × U(1) ψ . They include dumbbells, metastable strings, as well as domain walls bounded by necklaces. We provide
Rinku Maji, Qaisar Shafi, Amit Tiwari
doaj   +1 more source