Results 61 to 70 of about 327,247 (251)

Non-spinning tops are stable

Journal of High Energy Physics
We consider coupled gravitational and electromagnetic perturbations of a family of five-dimensional Einstein-Maxwell solutions that describes both magnetized black strings and horizonless topological stars.
Iosif Bena, Giorgio Di Russo, Jose Francisco Morales, Alejandro Ruipérez   +3 more
doaj   +1 more source

TN, Toda and Topological strings

, 2019
In this talk we will consider the long-standing problem of obtaining the 3-point functions of 2D Toda CFT. We will propose a solution to this problem employing topological strings and the AGT relation between 4D gauge theories and 2D ...
Pomoni, Elli
core   +1 more source

A Site‐Aware Representation Learning Framework For Unified Molecular Interaction Modeling and Generative Design

Advanced Science, EarlyView.
MolDBG is a site‐aware, sequence‐only framework that unifies drug‐target affinity prediction, binding‐site identification, and affinity‐conditioned molecular generation for structured proteins. Guided by multi‐task binding‐site supervision, it aligns interaction‐critical residues before learning drug‐target representations and simultaneously infers ...
Gang Luo, Qianqian Zhang, Chenhao Wang, Zhiheng Yi, Alex Jinpeng Wang, Jing Tang, Min Li   +6 more
wiley   +1 more source

Quantum periods and TBA-like equations for a class of Calabi-Yau geometries

Journal of High Energy Physics, 2021
We continue the study of a novel relation between quantum periods and TBA(Thermodynamic Bethe Ansatz)-like difference equations, generalize previous works to a large class of Calabi-Yau geometries described by three-term quantum operators.
Bao-ning Du, Min-xin Huang
doaj   +1 more source

Half-quantum vortices and walls bounded by strings in the polar-distorted phases of topological superfluid 3He

, 2019
| openaire: EC/H2020/694248/EU//TOPVACSymmetries of the physical world have guided formulation of fundamental laws, including relativistic quantum field theory and understanding of possible states of matter.
Rysti, Juho, Alexey, Yudin, Nissinen, Jaakko, Zhang, Kuang, Volovik, Grigory, Mäkinen, Jere, Dmitriev, Vlaidimir, Eltsov, Vladimir, G. E. Volovik, A. N. Yudin, Dmitriev, V. V., V. B. Eltsov, Eltsov, V. B., J. Rysti, J. T. Mäkinen, J. Nissinen, V. V. Dmitriev, Rysti, J., Nissinen, J., Volovik, G. E., Yudin, A. N., K. Zhang, Zhang, K., Mäkinen, J. T.   +23 more
core   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Phase transitions, double-scaling limit, and topological strings [PDF]

, 2020
Topological strings on Calabi--Yau manifolds are known to undergo phase transitions at small distances. We study this issue in the case of perturbative topological strings on local Calabi--Yau threefolds given by a bundle over a two-sphere.
Seminara, D, Griguolo, L, Marino, M, Caporaso, N, Pasquetti, S   +4 more
core   +3 more sources

A Unified Hierarchical Multiscale Fusion Framework for Drug–Target Affinity Prediction: From Benchmark Performance to Nanomolar Inhibitor Discovery

Advanced Science, EarlyView.
A multimodal fusion framework integrating sequence, atomic, and fragment representations captures drug–target interactions across multiple scales. The model delivers strong predictive performance and enables efficient virtual screening. Applied to hematopoietic progenitor kinase 1 (HPK1), it identifies structurally diverse inhibitors with nanomolar ...
Shuo Liu, Xiang Zhang, Haixia Feng, Yuquan Li, Xiaoqing Gong, Yong Liang, Xiaojun Yao, Huanxiang Liu   +7 more
wiley   +1 more source

Resonances and PT symmetry in quantum curves

Journal of High Energy Physics, 2020
In the correspondence between spectral problems and topological strings, it is natural to consider complex values for the string theory moduli. In the spectral theory side, this corresponds to non-Hermitian quantum curves with complex spectra and ...
Yoan Emery, Marcos Mariño, Massimiliano Ronzani   +2 more
doaj   +1 more source

Jacobi sigma models

Journal of High Energy Physics, 2021
We introduce a two-dimensional sigma model associated with a Jacobi manifold. The model is a generalisation of a Poisson sigma model providing a topological open string theory.
Francesco Bascone, Franco Pezzella, Patrizia Vitale   +2 more
doaj   +1 more source