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Differentially methylated topologically associating domains in brain tumors
2021In recent years, cancer has become one of the main causes of human death all over the world. Cancer is a generation of unhealthy cells that neither grow nor operate normally. Central nervous system (CNS) tumor is a creation of abnormal cells either in the spinal cord or in the brain.
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A Comparison of Topologically Associating Domain Callers Based on Hi-C Data
IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2023Jun Wang, Yaohang Li, Jianxin Wang
exaly
Exploring differential activation of topologically associating domains in cancer
2021ln the heart of eukaryotic cells, the nucleus encloses the genetic material that is transmitted over generations. ln human, this consists of 46 ONA molecules - ~2 m long when stretched out - com pacted to fit into a circular micrometer-scale structure. How this feat is achieved raises a longstand ing research topic.
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Topologically-Associating Domains: Gene Warehouses Adapted to Serve Transcriptional Regulation
Transcription, 2016Alexey Gavrilov +2 more
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Structure, Function and Evolution of Topologically Associating Domains (TADs) atHOX Loci
FEBS Letters, 2015Denis Duboule
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SuperTAD-Fast: Accelerating Topologically Associating Domains Detection Through Discretization
Journal of Computational BiologyShuai Cheng Li, Zhao Ling
exaly