Results 51 to 60 of about 61,406 (302)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Methods for designing the next generation of aircraft architectures using topology optimisation [PDF]

open access: yes, 2010
The need from energy efficient transportation has resulted in a growing interest in new aircraft configurations such as the Blended Wing Body. There is very little collective knowledge on the optimal structural layouts of these aircraft, and the ...
Eves, James, Eves, Jamie Samantha
core  

Design and experimental investigation of a novel thermal energy storage unit with phase change material

open access: yesEnergy Reports, 2021
A novel design of a shell-and-tube thermal energy storage unit with phase change material was proposed in the study. The layouts of highly conductive fins and phase change material (PCM) in the energy storage unit were optimized through the topology ...
Tingwei Zhang   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Configuration spaces of thick particles on graphs [PDF]

open access: yes, 2011
In this thesis, we study the topology of configuration spaces of particles of variable radius r>0 moving on a metric graph. Our main tool is a piecewise linear (PL) Morse-Bott theory for affine polytope complexes, which extends the Morse theory for such ...
DEELEY, KENNETH
core  

STRUCTURAL TOPOLOGY OPTIMIZATION FOR FLOOR BEAM OF RACK EMU BODY CONSIDERING MODAL FACTORS

open access: yesJixie qiangdu, 2022
The lightweight of rack EMU(Electric Multiple Units)body is one of the key factors to realize the strong climbing ability and comfort of rack EMU. Aiming at the lightweight design of rack EMU body floor beam, a structural design method combining 2 D with
CHEN RuiWen   +4 more
doaj  

ASCENT [PDF]

open access: yesACM SIGCOMM Computer Communication Review, 2002
Advances in microsensor and radio technology enable small but smart sensors to be deployed for a wide range of environmental monitoring applications. The low-per node cost allows these wireless networks of sensors and actuators to be densely distributed. The nodes in these dense networks coordinate to perform the distributed sensing and actuation tasks.
Cerpa, Alberto E, Estrin, D
openaire   +3 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Topology Optimization of Suction Muffler for Noise Attenuation [PDF]

open access: yes, 2012
A topology optimization method is developed to optimally design suction mufflers in reciprocating compressors. Suction mufflers should be designed for high noise reduction.
Choi, Dong Wook, Lee, Jin Woo
core   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

open access: yesFEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring   +3 more
wiley   +1 more source

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