Results 71 to 80 of about 1,164,927 (295)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Smooth constructions of homotopy-coherent actions

, 2022
We prove that, for nice classes of infinite-dimensional smooth groups G , natural constructions in smooth topology and symplectic topology yield homotopically coherent group actions of G . This yields a bridge between infinite-dimensional smooth groups
OH, YONG GEUN, Tanaka, Hiro Lee, Yong-Geun Oh   +2 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

A New Configuration of Three-Level ZSI Using Transistor Clamped Topology

Energies, 2020
In this paper, a three-level ZSI (impedance source inverter) based on transistor clamped theory is proposed. It uses the least number of switch counts and associated gate circuitry among all existing topologies of three-level ZSI without any performance ...
Santosh Sonar
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Numerical investigation of module-level inhomogeneous ageing in lithium-ion batteries from temperature gradients and electrical connection topologies

Communications Engineering
The distribution of current/voltage can be further regulated by optimising the electrical connection topology, considering a particular battery thermal management systems.
Haosong He, Ashley Fly, Edward Barbour, Xiangjie Chen   +3 more
doaj   +1 more source

Cascaded Multilevel Inverter Topology Based on Cascaded H-Bridge Multilevel Inverter

Energies, 2018
A three-phase multilevel inverter topology for use in various applications is proposed. The present topology introduces a combination of a cascaded H-bridge multilevel inverter with a cascaded three-phase voltage source inverter (three-phase triple ...
Abdullah M. Noman, Abdullrahman A. Al-Shamma’a, Khaled E. Addoweesh, Ayman A. Alabduljabbar, Abdulrahman I. Alolah   +4 more
doaj   +1 more source

Research on Strategy of DC Micro-grid Control and Protection

南方能源建设, 2020
[Introduction] The control and protection technology of DC microgrid plays an important role in ensuring the reliable and safe operation of DC microgrid. The paper aims to solve the key technologies in the design of DC micro-grid.
ZHOU Yu, ZHANG Hao, CHEN Rui, LU Lijuan, SHI Shihong   +4 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Topology optimisation: increasing the speed and reliability of design [PDF]

, 2014
In this paper, topology optimisation is applied to the design of the rear fuselage of an unmanned aerial vehicle (UAV). A comparison is drawn between the performance of a design created through evolutionary structural optimisation (ESO) and a baseline ...
Andy Keane, Keane, Andy J., Sobester, Andras, Liam M. Kelly, Andras Sobester, Kelly, Liam, David Toal, Toal, David J.J.   +7 more
core   +1 more source