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Treatment Patterns, Outcome, and Quality of Life of Patients With Extensive-Stage SCLC Receiving Third-Line Therapy-Data From the German CRISP Registry (AIO-TRK-0315): A Brief Report. [PDF]

JTO Clin Res Rep
Rost M, Fischer R, Reck M, Gauler T, Waller C, Christopoulos P, Hoffknecht P, Jänicke M, Fleitz A, Härzschel A, Lennartz C, Ludwig P, Groth A, Bendel M, Stratmann J, Griesinger F, Thomas M, Eberhardt WEE, Sebastian M.   +18 more
europepmc   +1 more source

Suvemcitug plus chemotherapy in women with platinum-resistant recurrent ovarian cancer: the SCORES randomized, double-blinded, phase 3 trial. [PDF]

Nat Cancer
Yuan G, Lou G, Li J, Xu M, Liu X, Wang D, Zhang K, Zhu T, Li X, Huang Y, Duan W, Wang K, Zhou Q, Li G, Yang C, Zhang J, Sun H, Tang R, Li Q, Wu L.   +19 more
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Intraocular Pressure Changes following Intravitreal Topotecan 90 μg/0.18 cc for the Treatment of Retinoblastoma. [PDF]

Ocul Oncol Pathol
Law CW, Francis JH, Abramson DH.
europepmc   +1 more source

Case Report: A case of diabetes mellitus and pneumonitis induced by envafolimab treatment in small cell lung cancer. [PDF]

Front Immunol
Li Y, Wang H, Xing G, Guo X, Yi S.
europepmc   +1 more source

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Isolation and structural confirmation of N -desmethyl topotecan, a metabolite of topotecan

Cancer Chemotherapy and Pharmacology, 1997
A sensitive high-performance liquid chromatography (HPLC) method for the determination of topotecan and total levels of topotecan (lactone plus its ring-opened hydroxycarboxylate form) was developed by the authors and used in several pharmacokinetics studies. During the analysis of plasma and urine samples collected in those studies, an additional peak
H Rosing, Beijnen J H, Rosing H
exaly   +4 more sources

Topotecan

Reactions Weekly, 2016
  +7 more sources

Clinical Pharmacokinetics of Topotecan

Clinical Pharmacokinetics, 1996
Topotecan (Hycamtin), a semisynthetic water-soluble derivative of camptothecin, is a potent inhibitor of DNA topoisomerase I in vitro and has demonstrated encouraging antitumour activity in a wide variety of tumours, including ovarian cancer and small cell lung cancer.
Herben, V.M.M., ten Bokkel Huinink, W.W., Beijnen, J.H.   +2 more
openaire   +3 more sources

Topotecan

Reactions Weekly, 2002
Ines Mader, Patrizia E. Fürst-Weger, Robert M. Mader, Elisabeth I. Semenitz, Robert Terkola, Sabine M. Wassertheurer   +5 more
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Topotecan in cervical cancer

International Journal of Gynecological Cancer, 2007
Recurrent and advanced cervical cancers are associated with high mortality and a lack of effective treatment options, especially for women who are poor candidates for surgery or radiation therapy. The broad clinical effectiveness and manageable toxicity of topotecan in other human malignancies as well as promising recent study results suggest that it ...
S, Ackermann, M W, Beckmann, F, Thiel, T, Bogenrieder   +3 more
openaire   +2 more sources