Results 161 to 170 of about 41,306 (245)

Mitigating growth-stress tradeoffs via elevated TOR signaling in rice. [PDF]

Mol Plant
Li W, Liu J, Li Z, Ye R, Chen W, Huang Y, Yuan Y, Zhang Y, Hu H, Zheng P, Fang Z, Tao Z, Song S, Pan R, Zhang J, Tu J, Sheen J, Du H.   +17 more
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, Volume 16, Issue 4, Page 803-813, April 2026.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Sirtulin-Ypk1 regulation axis governs the TOR signaling pathway and fungal pathogenicity in <i>Cryptococcus neoformans</i>. [PDF]

Microbiol Spectr
Chai Z, Li Y, Zhang J, Ding C, Tong X, Zhang Z.   +5 more
europepmc   +1 more source

Automated identification of radiotherapy treatment sites from unstructured physician notes

Journal of Applied Clinical Medical Physics, Volume 27, Issue 4, April 2026.
Abstract Purpose Ambiguous or incomplete documentation is a recurrent bottleneck in radiation oncology workflows, leading to inefficiencies in communication and potential treatment delays. Large language models (LLMs) pose a solution to addressing these ambiguities without added burden to clinical staff.
Klea Hoxha, Ricky R. Savjani, Jack Neylon, Jonathan Pham, Rojine Ariani, Dylan P. O'Connell   +5 more
wiley   +1 more source

Pulmonary Function Decline in Very Early Diagnosis of Systemic Sclerosis: A Retrospective Longitudinal Single‐Center Study

ACR Open Rheumatology, Volume 8, Issue 4, April 2026.
Objective The very early diagnosis of systemic sclerosis (SSc; VEDOSS) criteria aim to identify patients at risk of evolving into SSc. The predictive value of diffusing capacity of the lungs for carbon monoxide (DLco) and forced vital capacity (FVC) remains poorly characterized. This study aimed to evaluate whether baseline pulmonary function test (PFT)
Eugenio Capparelli, Greta Pellegrino, Eleonora Zaccara, Giorgio Bonardi, Elisabetta Ricchiuti, Daniele Colombo, Maria Sole Chimenti, Paola Faggioli, Antonino Mazzone   +8 more
wiley   +1 more source

Von Hippel-Lindau tumor suppressor (VHL) stimulates TOR signaling by interacting with phosphoinositide 3-kinase (PI3K). [PDF]

J Biol Chem, 2020
Hwang SH, Bang S, Kim W, Chung J.
europepmc   +1 more source

Natural Negative Feedback Loops Confer Indica‐Japonica Differentiation for Grain Size Homeostasis in Rice

Advanced Science, Volume 13, Issue 19, 2 April 2026.
This study reveals the genetic and molecular mechanisms controlling grain size homeostasis through fine‐tuning OsGRX8 self‐expression by two natural negative feedback loops functioning in redox‐dependent or ‐independent manners and identifies two self‐regulatory haplotypes (SRHs) for the subspecies differentiation in rice.
Xingxing Li, Meng‐en Wu, Ziqi Qiao, Junkui Huang, Juncheng Zhang, Yang Ding, Junqing Zhu, Jingyue Xu, Yuxin Huang, Wei Li, Xiaomin Su, Yue Ding, Jianwei Zhang, Yibo Li   +13 more
wiley   +1 more source

A Single Bout of Aerobic Exercise Increases Neuronal Extracellular Vesicle‐Derived Insulin Signaling Biomarkers in Adults With Cardiometabolic Risk

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
A single bout of aerobic exercise performed the night before increased some insulin signaling proteins classically involved in glucose metabolism as well as those implicated in neuronal cell growth and proliferation. We specifically observed that exercise may modulate some of these nEV‐derived biomarkers during the fasting and/or post‐glucose ingestion
Steven K. Malin, Daniel J. Battillo, Michal S. Beeri, Maja Mustapic, Dimitrios Kapogiannis   +4 more
wiley   +1 more source

TOR Signaling in Caenorhabditis elegans Development, Metabolism, and Aging. [PDF]

Genetics, 2019
Blackwell TK, Sewell AK, Wu Z, Han M.
europepmc   +1 more source

Photoperiod and temperature separately regulate nymphal development through JH and insulin/TOR signaling pathways in an insect. [PDF]

Proc Natl Acad Sci U S A, 2020
Miki T, Shinohara T, Chafino S, Noji S, Tomioka K.   +4 more
europepmc   +1 more source