Results 21 to 30 of about 41,306 (245)
TOR Signaling in Growth and Metabolism [PDF]
Cell, 2006 The target of rapamycin (TOR) is a conserved Ser/Thr kinase that regulates cell growth and metabolism in response to environmental cues. Here, highlighting contributions from studies in model organisms, we review mammalian TOR complexes and the signaling branches they mediate.
Wullschleger, S. +2 more
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Adiponectin impairs chicken preadipocytes differentiation through p38 MAPK/ATF-2 and TOR/p70 S6 kinase pathways. [PDF]
PLoS ONE, 2013 Adiponectin is a protein hormone secreted exclusively by adipocytes that plays an important role in the modulation of glucose and lipid metabolism.
Jun Yan, Lu Gan, Di Chen, Chao Sun
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Frontiers in Plant Science, 2016 Target of Rapamycin (TOR) signaling is an important regulator in multiple organisms including yeast, plants and animals. However, the TOR signaling in plants is much less understood as compared to that in yeast and animals.
Fangjie Xiong +9 more
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Diet and energy-sensing inputs affect TorC1-mediated axon misrouting but not TorC2-directed synapse growth in a Drosophila model of tuberous sclerosis. [PDF]
PLoS ONE, 2012 The Target of Rapamycin (TOR) growth regulatory system is influenced by a number of different inputs, including growth factor signaling, nutrient availability, and cellular energy levels.
Brian Dimitroff +8 more
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Evolutionarily conserved regulation of TOR signalling [PDF]
Journal of Biochemistry, 2013 The target of rapamycin (TOR) is an evolutionarily conserved protein kinase that regulates cell growth in response to various environmental as well as intracellular cues through the formation of 2 distinct TOR complexes (TORC), TORC1 and TORC2. Dysregulation of TORC1 and TORC2 activity is closely associated with various diseases, including diabetes ...
Terunao, Takahara, Tatsuya, Maeda
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Frontiers in Plant Science, 2015 Target of rapamycin (TOR) acts as a master regulator to control cell growth by integrating nutrient, energy, and growth factors in all eukaryotic species. TOR plays an evolutionarily conserved role in regulating the transcription of genes associated with
Pan eDong +6 more
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PLoS Genetics, 2022 The target of the rapamycin (TOR) signaling pathway plays a negative role in controlling virulence in phytopathogenic fungi. However, the actual targets involved in virulence are currently unknown.
Antonio de la Torre +1 more
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TOR signaling in mammals [PDF]
Journal of Cell Science, 2004 Central to the pathways that induce cell growth in mammals is the murine target of rapamycin (mTOR), a multi-domain, 298 kDa, evolutionarily-conserved Ser/Thr kinase that is inhibited by the drug rapamycin ([Schmelzle and Hall, 2000][1]).
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G3: Genes, Genomes, Genetics, 2018 Patterning of the Drosophila embryonic termini by the Torso (Tor) receptor pathway has long served as a valuable paradigm for understanding how receptor tyrosine kinase signaling is controlled.
Alex R. Johns +6 more
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The TOR Pathway Is Involved in Adventitious Root Formation in Arabidopsis and Potato
Frontiers in Plant Science, 2017 In the agriculture industry, adventitious root formation is a core issue of plants asexual propagation. However, the underlying molecular mechanism of adventitious root formation is far beyond understanding.
Kexuan Deng +10 more
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