Results 71 to 80 of about 41,306 (245)

Potyviruses differ in their requirement for TOR signalling

Journal of General Virology, 2015
Potyviruses are important plant pathogens that rely on many plant cellular processes for successful infection. TOR (target of rapamycin) signalling is a key eukaryotic energy-signalling pathway controlling many cellular processes such as translation and autophagy. The dependence of potyviruses on active TOR signalling was examined.
Ouibrahim, Laurence, Giner Rubio, Ana, Moretti, André, Montane, Marie-Helene, Menand, Benoît, Meyer, Christian, Robaglia, Christophe, Caranta, Carole   +7 more
openaire   +3 more sources

Dietary and biomarker‐guided strategies as supportive measures in the fragile X syndrome

Food Biomacromolecules, EarlyView.
Abstract The fragile X syndrome (FXS) is an inherited neurodevelopmental disorder that primarily affects males, often resulting in an IQ below 55, while about two‐thirds of females also experience intellectual disability. Physical features may include an elongated face, prominent ears, finger joint laxity, and enlarged testes in males.
Jailan E. El Halawani, Reem R. AlOlaby
wiley   +1 more source

Intraoperative Indocyanine Green Fluorescence Enables Primary Tumor Localization and Treatment De‐Escalation in SCCUP: A Case Report

Head &Neck, EarlyView.
ABSTRACT Background Unknown primary cancer in the head and neck presents a difficult surgical treatment dilemma. Patients with squamous cell carcinoma of unknown primary (SCCUP) typically present with an enlarging neck mass found on biopsy but with no indication of primary site on diagnostic exams such as flexible laryngoscopy, CT, MRI, and/or PET/CT ...
Nikhil Bellamkonda, Nitish Khurana, Eric Babajanian, Hamidreza Ghandehari, Jeremiah A. Alt, Richard B. Cannon   +5 more
wiley   +1 more source

Target of rapamycin is a key player for auxin signaling transduction in Arabidopsis

Frontiers in Plant Science, 2016
Target of rapamycin (TOR), a master sensor for growth factors and nutrition availability in eukaryotic species, is a specific target protein of rapamycin.
Kexuan eDeng, Lihua eYu, Xianzhe eZheng, Kang eZhang, Wanjing eWang, pan edong, Jiankui eZhang, Maozhi eRen   +7 more
doaj   +1 more source

Metroplasty before IVF in women with a T‐shaped uterus: A clinical challenge

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract A T‐shaped uterus is a uterine malformation, which can be either congenital or acquired, potentially impairing fertility and increasing the risk of miscarriage. Diagnosis primarily relies on three‐dimensional ultrasound and hysteroscopy. Hysteroscopic metroplasty is the standard surgical intervention aimed at restoring normal uterine anatomy ...
Fabio Barra, Irene Gazzo, Alessandro Favilli, Consuelo Russo, Giulia Monaco, Franco Alessandri, Sandro Gerli, Luis Alonso Pacheco, Caterina Exacoustos, Simone Ferrero   +9 more
wiley   +1 more source

A large‐scale single‐cell transcriptomic atlas indicates the immune panorama of influenza A infection

iMeta, EarlyView.
The study presents a large‐scale single‐cell transcriptomic atlas profiling over 612,010 peripheral immune cells from 97 individuals to decode the heterogeneity of influenza infection. These findings indicate a fundamental immune dichotomy determining clinical trajectories: a protective, monocyte‐centric antiviral state in mild disease versus a ...
Yi Wang, Shuzi Liu, Laurence Don Wai Luu, Yongzhi Zhai, Chenliang Zhu, Zhaomin Feng, Yao Tan, Linglong Wan, Jie Wang, Juan Zhou, Jing Wang, Lixin Xie, Quanyi Wang, Fei Xie   +13 more
wiley   +1 more source

Holocene sea‐level and environmental changes on the Isle of Mull, Scotland

Journal of Quaternary Science, EarlyView.
ABSTRACT Sea‐level and coastal changes are reconstructed on the Isle of Mull, western Scotland, from 10 988 to 10 507 cal BP to the present. This research has produced the first SLIP for the Isle of Mull. A multiproxy approach including pollen, spore, foraminifera and diatom analyses reveals palaeoenvironmental changes from two coastal sites.
Katherine A. Selby, Jane Wheeler, William E. N. Austin, Heather Austin, Tom Hill, Sarah L. Bradley, Sally Derrett   +6 more
wiley   +1 more source

Functional Characterization of Target of Rapamycin Signaling in Verticillium dahliae

Frontiers in Microbiology, 2019
More than 200 plants have been suffering from Verticillium wilt caused by Verticillium dahliae (V. dahliae) across the world. The target of rapamycin (TOR) is a lethal gene and controls cell growth and development in various eukaryotes, but little is ...
Linxuan Li, Tingting Zhu, Yun Song, Yun Song, Xiumei Luo, Li Feng, Fengping Zhuo, Fengping Zhuo, Fuguang Li, Fuguang Li, Maozhi Ren   +10 more
doaj   +1 more source

Robustness Assessment of Public Transport Networks in Various Graph Representations: Systematic Review, Decision Support, and Case Study

Networks, EarlyView.
ABSTRACT The analysis of certain properties of the underlying graph of a public transport network generates insights about the network's structure. Hereby, the choice of the graph representation depends on a trade‐off between complexity reduction and information preservation to adequately model a public transport network.
Michael Palk, Stefan Voß, Raka Jovanovic   +2 more
wiley   +1 more source

Caloric restriction‐mediated reproductive lifespan extension across multiple strains of the clonal aquatic plant Lemna turionifera

Oikos, EarlyView.
Lifespan extension due to caloric restriction (CR) is a well‐established aspect of animal senescence that has been observed in many taxa. Contrastingly, there is much less evidence in plants, even though it is straightforward to manipulate CR by restricting photosynthesis through reduction in light intensity.
Julian A. Ketler, Nicola M. Herman, Suzanne L. Chmilar, Robert A. Laird   +3 more
wiley   +1 more source