Results 51 to 60 of about 466,154 (153)

Short-Coupled Variant of "Torsades de Pointes" and Polymorphic Ventricular Tachycardia

Arquivos Brasileiros de Cardiologia, 2014
"Torsades de pointes" (TdP) ventricular tachycardias carry a high risk of sudden death, even when they occur in individuals with a structurally normal heart, in the absence of myocardial ischemia or prolonged QT interval. Leenhardt et al1 described a new
M. Chokr, F. Darrieux, C. Hardy, D. Hachul, Allisson Valadão de Oliveira Britto, S. L. de Melo, C. Pisani, E. Sosa, M. Martinelli, M. Scanavacca   +9 more
semanticscholar   +1 more source

Fluconazole‐Induced Electrolyte Disturbances and Cardiac Toxicity in a CRRT‐Dependent Patient With Acute Renal Failure

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Fluconazole is a commonly used antifungal drug in clinical practice. Both hyperkalemia and QT interval prolongation are life‐threatening complications of fluconazole. Our report warns clinicians to pay attention to the cardiotoxicity and electrolyte disorders of fluconazole when using it to avoid serious consequences.
Fuxia Jian, YuShan Zhang, Shili Zhong, Zhen Wang, Cui Shang   +4 more
wiley   +1 more source

Aripiprazole overdose in Hong Kong: A 10‐year retrospective cohort

Hong Kong Journal of Emergency Medicine, Volume 32, Issue 5, October 2025.
Abstract Introduction Aripiprazole is considered to have a favourable safety profile in overdose, with low risks of cardiovascular and neurological toxicity. However, local data are limited, and the impact of co‐ingestants remains insufficiently studied.
Tun Kin Lam, Shan Liu, Chun Fai Hui
wiley   +1 more source

Identifying Pediatric Drug Safety Knowledge Gaps: An Integrated Approach Leveraging Real‐World Data, a Biomedical Knowledge Base, and Postmarketing Surveillance Data

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 45, Issue 10, Page 667-676, October 2025.
ABSTRACT Background Drug safety has historically been understudied in pediatric populations, rendering them “therapeutic orphans.” Pediatric drug indications and dosages are often inferred by extrapolating safety, efficacy, and dosing data from adult studies, leading to widespread off‐label use.
Saurabh Rahurkar, Jiayi Ouyang, Pallavi Jonnalagadda, Xiaofu Liu, Shijun Zhang, Chien‐Wei Chiang, Lei Wang, Aditi Shendre, Lang Li   +8 more
wiley   +1 more source

Case Report of Long QT Syndrome in a Patient With Syncope

The Kaohsiung Journal of Medical Sciences, EarlyView.
Chun‐Yu Chen, Rui‐Xian Wang, Ken‐Pen Weng, Shih‐Ming Huang   +3 more
wiley   +1 more source

No Evidence of QTc Interval Prolongation With Baxdrostat Treatment: Concentration–QTc Modeling Assessment

Pharmacology Research &Perspectives, Volume 13, Issue 5, October 2025.
We present concentration‐QTc modeling analyses from two phase 1 studies of the novel, highly selective aldosterone synthase inhibitor, baxdrostat. The assessments presented here confirm the lack of QT‐interval prolongation risk with baxdrostat at therapeutic and supra‐therapeutic concentrations. ABSTRACT Baxdrostat is a novel, highly potent, selective,
Mikael Sunnåker, Christian Källgren, Joanna Parkinson, Corina Dota, Christer Gottfridsson, David Janzén, Anita Andersson, Glenn Carlson   +7 more
wiley   +1 more source

THE FIRST EXPERIENCE OF IMPLANTED CARDIOVERTER/ DEFIBRILLATOR IN A PATIENT WITH LIFE-THREATENING TORSADES DE POINTES

Российский кардиологический журнал, 2002
The first experience of implanted cardioverter/ defibrillator in a patient with life-threatening torsades de pointes.
E. V. Kolpakov, V. V. Slobodiannik, I. A. Mochkin, M. G. Lukava   +3 more
doaj  

Adrenal and extra-adrenal pheochromocytomas presenting as life-threatening ventricular arrhythmias: Report of three cases

Indian Heart Journal, 2016
Pheochromocytoma patients can rarely have prolonged QT interval in the ECG. We report three cases of pheochromocytoma in females presenting with ventricular arrhythmia; two had torsades de pointes and a third patient had frequent VPCs and nonsustained ...
Sai Satish Oruganti
doaj   +1 more source

The impact of plasma glucose decline rate on cardiac repolarisation in individuals with type 1 diabetes

Diabetes, Obesity and Metabolism, Volume 27, Issue 10, Page 5587-5598, October 2025.
Abstract Aims To investigate whether plasma glucose decline rates influence cardiac repolarisation, transmural dispersion and counterregulatory hormones in individuals with type 1 diabetes (T1D) with and without good glycaemic control. Materials and Methods In a randomised crossover study, 20 young men with T1D (10 well‐regulated (HbA1c ≤53 mmol/mol ...
Per G. Hagelqvist, Christine R. Schwarz, Kaisar Maytham, Yasmin H. Hamid, Tommi B. Lindhardt, Bolette Hartmann, Filip K. Knop, Andreas Andersen, Tina Vilsbøll   +8 more
wiley   +1 more source

A Cardiac Magnetic Resonance–Based Risk Stratification for Life‐Threatening Ventricular Tachyarrhythmias in Heart Failure: The SNE2 Score

NMR in Biomedicine, Volume 38, Issue 9, September 2025.
The presence of LGE, syncope, and nonsustained ventricular tachycardia were identified as risk markers of LTVTA. A total score of ≥ 3 was considered high risk. The novel scoring model may assist in the preliminary screening of patients with symptomatic heart failure with a potentially elevated risk. ABSTRACT Risk stratification for sudden cardiac death
Xing Xing, Xiaofei Li, Xiaohan Fan, Xiaoqiang Liu, Yi Zhang, Lei Zhang, Yan Yao, Fang Wang   +7 more
wiley   +1 more source