Results 161 to 170 of about 3,074 (210)

Torsemide: A new loop diuretic

American Journal of Health-System Pharmacy, 1995
The pharmacology, pharmacokinetics, clinical efficacy, adverse effects, and dosage and administration of torsemide are reviewed. Torsemide belongs to the pyridine-sulfonylurea class of loop diuretics. Its primary site of activity is the thick ascending limb of the loop of Henle, where it blocks active reabsorption of sodium and chloride, resulting in ...
S F, Fowler, K M, Murray
exaly   +4 more sources

Torsemide inhibits aldosterone secretion in vitro

Life Sciences, 1998
Torsemide inhibited aldosterone secretion by adrenal cells from rats, cows, and guinea pigs stimulated in vitro by potassium, angiotensin, dibutyryl cyclic AMP, ACTH, or corticosterone. Inhibitory concentrations for adrenal cells (micromolar) were comparable with those reported to inhibit ion transport in isolated renal tubules.
T L, Goodfriend, D L, Ball, W, Oelkers, V, Bähr   +3 more
exaly   +3 more sources

Torsemide Crystalline Salts with a Significant Spring-Parachute Effect

AAPS PharmSciTech
Torsemide is a long acting pyridine sulfonylurea diuretic. Torsemide hydrochloride is widely used now, there are only a few organic acid salts reported. Cocrystallization with organic acids is an effective way to improve its solubility. Here, we reported maleate and phthalate of torsemide, in which the organic acid lost a proton transferring to the ...
Xuezhen Deng, Weimin Shi, Kun Qian, Jie Yang, Siyu Yuan, Hong Li   +5 more
exaly   +3 more sources

Probable Interaction Between Warfarin and Torsemide

Annals of Pharmacotherapy, 2008
Objective:To report a case in which the anticoagulation effect of warfarin appeared to be potentiated by torsemide, possibly due to an interference of metabolism through competition for the CYP2C9 isoenzyme and protein-binding displacement of warfarin.Case Summary:A 43-year-old Hispanic female with congestive heart failure, hypothyroidism, anemia ...
Jennifer, Bird, Carlos, Carmona
openaire   +2 more sources

Torsemide: A Pyridine-Sulfonylurea Loop Diuretic

Annals of Pharmacotherapy, 1995
Objective:To review the clinical pharmacology of torsemide and to compare it with currently available loop diuretics, particularly furosemide.Data Sources:An English-language MEDLINE search, 1985 to October 1994, was used to identify pertinent literature, including review articles.Data Extraction:Data from scientific literature were extracted ...
J S, Blose, K F, Adams, J H, Patterson
openaire   +2 more sources

Hypokalaemic quadriparesis following torsemide and spironolactone use

The National Medical Journal of India, 2018
Mild hypokalaemia is a common electrolyte abnormality following therapeutic doses of diuretics such as torsemide. If undiagnosed and untreated, hypokalaemia progresses and smooth muscle, skeletal muscle and the heart are affected. Potassium-sparing diuretics such as spironolactone are commonly added to loop diuretics to prevent symptomatic hypokalaemia.
Upinder, Kaur, Sankha Shubhra, Chakrabarti, Ashis Kumar, Choudhury, Indrajeet Singh, Gambhir   +3 more
openaire   +2 more sources

Torsemide in the Management of Pulmonary Edema

Journal of The Association of Physicians of India
Pulmonary edema, either cardiogenic or noncardiogenic, is caused by fluid accumulation in the alveolar spaces. Cardiogenic pulmonary edema (CPE), one of the causes of congestive heart failure (CHF), is treated with loop diuretics. Torsemide and furosemide were found to be useful in the treatment of CHF-associated pulmonary edema due to their ability to
Agam, Vora, Amit, Sharma, , Sivakadaksham, R H, Sundar, Sankar Chandra, Mandal, Nandini, Chatterjee, Animesh, Agarwal, Mukul Kumar, Bhatnagar, Abhishek, Gupta, Rajinder, Thaploo, Febin, Francis, Senthilnathan, Mohanasundaram   +11 more
openaire   +2 more sources

Torsemide in Edema Associated with Hepatic Impairment

Journal of The Association of Physicians of India
Hepatic edema is caused by decreased hepatic protein synthesis, a consequence of decompensated liver cirrhosis. Fluid accumulation occurs when there is an increase in hydrostatic pressure in the hepatic sinusoids and splanchnic capillaries, as well as low albumin.
Rajesh, Upadhyay, Mangesh, Tiwaskar, Ramesh, Dargad, Udas, Ghosh, Dev Kumar, Jain, Raghu Kishore, Galla, Guguloth, Haricharan, Jayanta, Sharma, Mayank, Thakker, Nitin, Zalte, Senthilnathan, Mohanasundaram   +10 more
openaire   +2 more sources

Torsemide in the Management of Essential Hypertension

Journal of The Association of Physicians of India
Torsemide, a loop diuretic, is increasingly recognized for its role in managing essential hypertension. Its mechanism of action involves inhibiting the reabsorption of sodium and chloride ions in the ascending loop of Henle in the kidneys. By doing so, torsemide promotes diuresis, which refers to increased urine production, and subsequently lowers ...
Kuntal, Bhattacharyya, Mangesh, Tiwaskar, Arnab, Datta, Arti Lal, Chandani, Santosh Kumar, Agrawal, Jabir, Abdullakutty, Rajesh, Badani, Dhaval, Doshi, Vikas, Singh, Prashant, Advani, Kiron, Varghese, Ajay Kumar, Pandey, Febin, Francis, Amarnath, Sugumaran   +13 more
openaire   +2 more sources