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Prognostic relevance of short-term changes in body weight, renal indices, and echocardiographic variables after intravenous diuretic therapy in dogs with myxomatous mitral valve disease hospitalized for pulmonary edema. [PDF]
Vet QPark SW, You KH, Kim K, Ro WB, Lee CM.
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Torsemide: a new loop diuretic.
American Journal of Health-System Pharmacy, 1995The pharmacology, pharmacokinetics, clinical efficacy, adverse effects, and dosage and administration of torsemide are reviewed. Torsemide belongs to the pyridine-sulfonylurea class of loop diuretics. Its primary site of activity is the thick ascending limb of the loop of Henle, where it blocks active reabsorption of sodium and chloride, resulting in ...
Kim M Murray
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Torsemide inhibits aldosterone secretion in vitro
Life Sciences, 1998Torsemide inhibited aldosterone secretion by adrenal cells from rats, cows, and guinea pigs stimulated in vitro by potassium, angiotensin, dibutyryl cyclic AMP, ACTH, or corticosterone. Inhibitory concentrations for adrenal cells (micromolar) were comparable with those reported to inhibit ion transport in isolated renal tubules.
Theodore L Goodfriend, D L Ball, V Bahr
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Evaluation of the effect of torsemide on warfarin dosage requirements
International Journal of Clinical Pharmacy, 2017Background According to drug interaction databases, torsemide may potentiate the effects of warfarin. Evidence for this drug-drug interaction, however, is conflicting and the clinical significance is unknown. Objective The aim of this study is to evaluate the impact of torsemide initiation on warfarin dosage requirements.
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Comparative Effectiveness of Torsemide Versus Furosemide in Heart Failure Patients: Insights From the Protect Trial [PDF]
Future Cardiology, 2015 The authors assessed the comparative effectiveness of torsemide versus furosemide in the PROTECT ...
Marco Metra +2 more
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British Journal of Clinical Pharmacology, 2006 AIMS: To investigate the association between torsemide renal clearance and genetic variation in the basolaterally expressed renal organic anion transporters OAT1 and OAT3 and in the luminally situated OAT4.
Peter Nürnberg +2 more
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Torsemide: A Pyridine-Sulfonylurea Loop Diuretic
Annals of Pharmacotherapy, 1995Objective: To review the clinical pharmacology of torsemide and to compare it with currently available loop diuretics, particularly furosemide. Data Sources: An English-language MEDLINE search, 1985 to October 1994, was used to ...
J S, Blose, K F, Adams, J H, Patterson
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