Results 121 to 130 of about 1,957 (165)

Torsemide: A Pyridine-Sulfonylurea Loop Diuretic

Annals of Pharmacotherapy, 1995
Objective: To review the clinical pharmacology of torsemide and to compare it with currently available loop diuretics, particularly furosemide. Data Sources: An English-language MEDLINE search, 1985 to October 1994, was used to ...
J S, Blose, K F, Adams, J H, Patterson
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Torsemide in the Management of Essential Hypertension

Journal of The Association of Physicians of India
Torsemide, a loop diuretic, is increasingly recognized for its role in managing essential hypertension. Its mechanism of action involves inhibiting the reabsorption of sodium and chloride ions in the ascending loop of Henle in the kidneys. By doing so, torsemide promotes diuresis, which refers to increased urine production, and subsequently lowers ...
Kuntal, Bhattacharyya, Mangesh, Tiwaskar, Arnab, Datta, Arti Lal, Chandani, Santosh Kumar, Agrawal, Jabir, Abdullakutty, Rajesh, Badani, Dhaval, Doshi, Vikas, Singh, Prashant, Advani, Kiron, Varghese, Ajay Kumar, Pandey, Febin, Francis, Amarnath, Sugumaran   +13 more
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Torsemide in the Management of Pulmonary Edema

Journal of The Association of Physicians of India
Pulmonary edema, either cardiogenic or noncardiogenic, is caused by fluid accumulation in the alveolar spaces. Cardiogenic pulmonary edema (CPE), one of the causes of congestive heart failure (CHF), is treated with loop diuretics. Torsemide and furosemide were found to be useful in the treatment of CHF-associated pulmonary edema due to their ability to
Agam, Vora, Amit, Sharma, , Sivakadaksham, R H, Sundar, Sankar Chandra, Mandal, Nandini, Chatterjee, Animesh, Agarwal, Mukul Kumar, Bhatnagar, Abhishek, Gupta, Rajinder, Thaploo, Febin, Francis, Senthilnathan, Mohanasundaram   +11 more
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Torsemide in Edema Associated with Hepatic Impairment

Journal of The Association of Physicians of India
Hepatic edema is caused by decreased hepatic protein synthesis, a consequence of decompensated liver cirrhosis. Fluid accumulation occurs when there is an increase in hydrostatic pressure in the hepatic sinusoids and splanchnic capillaries, as well as low albumin.
Rajesh, Upadhyay, Mangesh, Tiwaskar, Ramesh, Dargad, Udas, Ghosh, Dev Kumar, Jain, Raghu Kishore, Galla, Guguloth, Haricharan, Jayanta, Sharma, Mayank, Thakker, Nitin, Zalte, Senthilnathan, Mohanasundaram   +10 more
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The pharmacodynamics of torsemide in patients with congestive heart failure

Clinical Pharmacology and Therapeutics, 1994
The pharmacodynamics of torsemide (a new loop diuretic of the pyridine sulfonylurea class) was studied in 16 subjects who had compensated congestive heart failure and had been receiving stable diuretic therapy. Oral doses of 50, 100, and 200 mg were studied by use of a randomized crossover design.
D, Vargo, W G, Kramer, P K, Black, W B, Smith, T, Serpas, D C, Brater   +5 more
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EFFECT OF FOOD ON THE PHARMACOKINETICS AND PHARMACODYNAMICS OF TORSEMIDE

American Journal of Therapeutics, 1995
The effect of food on the bioavailability, pharmacokinetics, and pharmacodynamics of oral torsemide was examined in a group of 14 healthy male volunteers. Administration of torsemide with a standard high-fat, high-carbohydrate breakfast resulted in a decrease in absorption rate (fed: C(max) 988 plus minus 269 ng ml(minus sign1), T(max) 1.50 plus minus ...
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Bioavailability, pharmacokinetics, and pharmacodynamics of torsemide in patients with cirrhosis

Clinical Pharmacology and Therapeutics, 1993
The bioavailability, pharmacokinetics, and pharmacodynamics of torsemide (10 mg orally and intravenously) were determined in a randomized crossover clinical trial with 12 patients with ascites caused by cirrhosis. Torsemide was rapidly absorbed with a bioavailability of 96.3% (confidence interval, 84% to 109%).
S, Schwartz, D C, Brater, D, Pound, P K, Green, W G, Kramer, D, Rudy   +5 more
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Hypokalaemic quadriparesis following torsemide and spironolactone use

The National Medical Journal of India, 2018
Mild hypokalaemia is a common electrolyte abnormality following therapeutic doses of diuretics such as torsemide. If undiagnosed and untreated, hypokalaemia progresses and smooth muscle, skeletal muscle and the heart are affected. Potassium-sparing diuretics such as spironolactone are commonly added to loop diuretics to prevent symptomatic hypokalaemia.
Upinder, Kaur, Sankha Shubhra, Chakrabarti, Ashis Kumar, Choudhury, Indrajeet Singh, Gambhir   +3 more
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Torsemide

2021
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Torsemide in Edema Associated with Chronic Kidney Disease

Journal of The Association of Physicians of India
Torsemide is a loop diuretic used to manage edema associated with chronic kidney disease (CKD) and acute kidney injury (AKI). It acts by inhibiting sodium and chloride ions reabsorption in the ascending limb of the loop of Henle, thereby increasing urine output and reducing fluid accumulation.
Deodatta, Chafekar, Pinaki, Mukhopadhyay, Niranjan, Ambekar, Shashi, Kumar, Jacob, George, Dinesh, Khullar, Sandip, Saxena, Jay, Shah, Sidharth, Mavani, Vivek, Ruhela, Manish, Goyal, Febin, Francis, Senthilnathan, Mohanasundaram   +12 more
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