Results 31 to 40 of about 1,146,764 (302)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Bioelectrical Impedance Analysis for Monitoring Fluid and Body Cell Mass Changes in Patients Undergoing Cardiopulmonary Bypass [PDF]

Brazilian Journal of Cardiovascular Surgery, 2020
Objective: To evaluate preoperative and postoperative body fluid distribution with a bioelectrical impedance analyzer in patients undergoing cardiopulmonary bypass.
Mustafa Göz, Cemil Sert, Abdussamet Hazar, Mehmet Salih Aydın, Nazim Kankılıç   +4 more
doaj   +2 more sources

Body condition of shorebirds upon arrival at their Siberian breeding grounds

, 2009
Arctic breeding shorebirds carry substantial body stores on their long-distance migrations from their non-breeding grounds. Upon arrival at the breeding area the remains of these stores can be used for egg formation, insurance against poor feeding ...
Klaassen, Raymond, Tulp, Ingrid, Visser, G. Henk, Klaassen, Raymond H. G., Ens, Bruno J., Ens, B.J., Tulp, I., Schekkerman, H., Visser, G.H., Schekkerman, Hans, Tulp, I.Y.M., Klaassen, R.H.G.   +11 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

High sodium intake and fluid overhydration predict cardiac structural and functional impairments in chronic kidney disease

Frontiers in Nutrition
BackgroundHigh sodium intake and fluid overhydration are common factors of and strongly associated with adverse outcomes in chronic kidney disease (CKD) patients. Yet, their effects on cardiac dysfunction remain unclear.AimsThe study aimed to explore the
Suyan Duan, Yuchen Ma, Fang Lu, Chengning Zhang, Honglei Guo, Ming Zeng, Bin Sun, Yanggang Yuan, Changying Xing, Huijuan Mao, Bo Zhang   +10 more
doaj   +1 more source

Evaluation by electrical bioimpedance method of selected morphological parameters of the body of women aged 19 to 26 not engaging in physical activity

Annales Academiae Medicae Silesiensis, 2022
Introduction Inadequate nutrition and a lack of physical activity contribute to the development of many diseases, which may not be clinically manifested at first, therefore the regular monitoring of health is essential for its preservation.
Beata Całyniuk, Agata Malczyk
doaj   +1 more source

Effect of an individually tailored one-year energy balance programme on body weight, body composition and lifestyle in recent retirees: a cluster randomised controlled trial [PDF]

, 2010
Background The increased prevalence of overweight and obesity warrants preventive actions, particularly among people in transitional stages associated with lifestyle changes, such as occupational retirement.
Albertine J Schuit, Werkman Andrea, Kok, F.J., Schuit, A.J., Evert G Schouten, Hulshof Paul JM, Kremers, S.P., Kremers, S.P.J., Werkman, A.M., Hulshof, P.J.M., Andrea Werkman, Schuit Albertine J, Stafleu, A., Werkman, A, Annette Stafleu, Kremers Stef PJ, Schouten Evert G, Werkman, A., Hulshof, P.J., Stafleu Annette, Paul JM Hulshof, Schouten, E.G., Kok Frans J, Frans J Kok, Stef PJ Kremers   +24 more
core   +1 more source

Groundwater Withdrawals Associated with Oil and Gas Production from Water Supply Aquifers in Texas: Implications for Water Management Practices

, 2021
The demand for water is continuing to increase as population and industry grow. The Natural Resources Defense Council indicated that Texas is at “extreme risk” for implementation of sustainable water management practices especially since groundwater is ...
Kristine Uhlman, Dorina Murgulet, Vickers, C., Uhlman, K., Coeckelenbergh, Katie, Chris Vickers, Vickers, Chris, Katie Coeckelenbergh, Coeckelenbergh, K., Murgulet, Dorina, Uhlman , Kristine, Murgulet, D.   +11 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source