Results 41 to 50 of about 14,812,424 (298)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Total body water and recurrent atrial fibrillation

Терапевтический архив, 2011
Aim. To specify the relationship between content of total body water and recurrent atrial fibrillation (AF) of non-valvular etiology. Material and methods.
Maksim Vital'evich Menzorov, Aleksandr Mikhaylovich Shutov, Valeriy Anatol'evich Serov, M V Menzorov, A M Shutov, V A Serov   +5 more
doaj  

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Body Composition Analysis in Obstructive Sleep Apnea: A Cross‐Sectional Study Using Bioelectrical Impedance Analysis

The Clinical Respiratory Journal
Introduction Obstructive sleep apnea (OSA) is a prevalent disorder characterized by recurrent upper airway collapse, resulting in intermittent hypoxia and sleep fragmentation.
Mucahit Yetim, Macit Kalçık, Lütfü Bekar, Yusuf Karavelioğlu, Yasemin Arı Yılmaz   +4 more
doaj   +1 more source

Poor haemoglobin-haematocrit agreement in apparently healthy adult population; a cross-sectional study in Cape Coast Metropolis, Ghana

Heliyon, 2021
Background: This study estimated total body water (TBW), daily water intake (DWI) and haemoglobin-haematocrit relationship in adults in a tropical environment where active lifestyles could precipitate plasma volume contraction.
Grace Ali-Baya, Emmanuel Zenile, Bridgette Obuor Aikins, Regina Elorm Amoaning, David Larbi Simpong, Patrick Adu   +5 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Effect of water restriction on drinking behaviour and water intake in German black-head mutton sheep and Boer goats

Animal, 2012
The present study was conducted to evaluate and compare the physiological responses of sheep and goats to water restriction using the deuterium dilution technique (D2O) to predict the total water intake (TWI) in both species.
D. Al-Ramamneh, A. Riek, M. Gerken
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Comparison of the Watson formula and bioimpedance spectroscopy for measuring body volume and calculating kt/V in patients with peritoneal dialysis

Renal Failure
Background Ascertaining the total body water (V), usually obtained by the Watson formula or bioimpedance spectroscopy (BIS), is crucial for the calculation of Kt/V in patients with peritoneal dialysis (PD).
Sixiu Liu, Yuan Feng, Qingyan Zhang, Jian Lu, Nan Li, Ying Liu, Chunming Jiang   +6 more
doaj   +1 more source