Results 51 to 60 of about 14,812,424 (298)
Deuterium oxide dilution accurately predicts water intake in sheep and goats
Animal, 2010 The aim of this study was to test whether the deuterium oxide dilution technique accurately predicts water intake in sheep and goats. Two other issues were also studied: (i) a comparison of water intake in sheep and goats and (ii) an assessment of ...
D. Al-Ramamneh, A. Riek, M. Gerken
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Total Body Water in Rats and in Mice
Experimental Biology and Medicine, 1954 Summary and ConclusionsTotal body water by vacuum desiccation, total body fat by ether extraction, and fat-free dry body weight were measured in normal mice and rats, and in starved and dehydrated rats. In normal animals total body water was not shown to differ from a direct proportion of fat-free dry weight, and body fat was not shown to have an ...
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
COMPARATIVE ANALYSIS OF BODY COMPOSITION [PDF]
Bulletin of the Transilvania University of Braşov: Series IX Sciences of Human Kinetics, 2018 The analysis of body composition is a broadly applied approach used to evaluate the health condition of the human body, with a view to improving the quality of life, physical activity and sport performance.
Carmen GUGU-GRAMATOPOL1
doaj
Measurement of Total Body Water in the Dog with Antipyrine.
Experimental Biology and Medicine, 1952 Summary and Conclusions1. Intravenously injected antipyrine is destroyed in the dog at the rate of 20 to 60% per hour. 2. Nevertheless, antipyrine space may be used for the determination of total body water in the dog, because of the fact that the distribution of antipyrine appears to be essentially complete after 10 minutes. 3.
M, HERROLD, L A, SAPIRSTEIN
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Anthropometric and physiological changes in elite female water polo players during a training year [PDF]
, 2008 The aim of the current study was to monitor physiological and anthropometric characteristics of elite female water polo players within the periodized training year. Fourteen subjects participated in the current study.
Marrin, K. +3 more
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source