Results 61 to 70 of about 1,146,764 (302)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Longitudinal changes in body composition with advancing pregnancy and the relationship of maternal fat deposition to fetal growth. [PDF]
, 1996 Obesity has long been recognised as a risk factor for the development of variety of life threatening diseases; examples include diabetes mellitus and cardio vascular disease.
Soltani-Karbaschi, Hora +1 more
core
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
COMPARATIVE ANALYSIS OF BODY COMPOSITION [PDF]
Bulletin of the Transilvania University of Braşov: Series IX Sciences of Human Kinetics, 2018 The analysis of body composition is a broadly applied approach used to evaluate the health condition of the human body, with a view to improving the quality of life, physical activity and sport performance.
Carmen GUGU-GRAMATOPOL1
doaj
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Measurement of Total Body Water in the Dog with Antipyrine.
Experimental Biology and Medicine, 1952 Summary and Conclusions1. Intravenously injected antipyrine is destroyed in the dog at the rate of 20 to 60% per hour. 2. Nevertheless, antipyrine space may be used for the determination of total body water in the dog, because of the fact that the distribution of antipyrine appears to be essentially complete after 10 minutes. 3.
M, HERROLD, L A, SAPIRSTEIN
openaire +2 more sources
Comparison of different methods for estimating total body water when describing mass and fluid transfer in dialysis [PDF]
, 2022 LAUREA MAGISTRALENegli anni ci si sta concentrando sempre di più sullo sviluppo di trattamenti personalizzati per quanto riguarda l’emodialisi. Per riuscire in questo intento, sono stati sviluppati vari modelli matematici, in grado di stimare, per tutta
GASI, LEONARD
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
, 2004 Objective: To investigate the accuracy of total body water (TBW) predicted by foot-to-foot bioelectrical impedance compared with a deuterium oxide dilution technique in oncology outpatients receiving ...
Davies, P.S.W. +7 more
core +1 more source